化学信息学-数据库.pptx

ACS数据库 第一篇 题目:A Highly Selective Ratiometric?Two-Photon?Fluorescent?Probe?for Human Cytochrome P450 1A 作者:Zi-Ru Dai?, Guang-Bo Ge??, Lei Feng??, Jing Ning?, Liang-Hai Hu⊥, Qiang Jin?, Dan-Dan Wang?, Xia Lv?, Tong-Yi Dou?, Jing-Nan Cui*?, and Ling Yang*? 摘要:Cytochrome P450 1A (CYP1A), one of the most important phase I drug-metabolizing enzymes in humans, plays a crucial role in the metabolic activation of procarcinogenic compounds to their ultimate carcinogens. Herein, we reported the development of a ratiometric?two-photonfluorescent?probe?NCMN?that allowed for selective and sensitive detectio