贝那普利联合美托洛尔治疗扩张型心肌病心力衰竭临床探析.docVIP

贝那普利联合美托洛尔治疗扩张型心肌病心力衰竭临床探析 　　[摘要]目的 探讨贝那普利联合美托洛尔治疗扩张型心肌病心力衰竭的临床效果。方法 分析东莞市厚街医院心血管内科2014年1月～2016年1月心内科收治的扩张型心肌病心力衰竭患者60例临床资料，依据治疗方式不同进行分组，对照组（洋地黄联合美托洛尔治疗组）30例和观察组（贝那普利联合美托洛尔治疗组）30例。观察两组患者治疗前后心功能、肺功能情况，观察两组患者临床疗效情况。结果 两组患者治疗前左心房内径、左心室舒张末径、左心室射血分数、6 min行走距离、FEV1、FEV1/FVC、FEV1%比较，差异无统计学意义（P0.05），治疗后两组患者各指标均优于治疗前，且观察组治疗后患者各指标均优于对照组（P0.05）。?Y论 贝那普利联合美托洛尔治疗扩张型心肌病心力衰竭患者，可以明显改善患者的心功能、肺功能，提高临床疗效，值得临床推广应用 [关键词]贝那普利；美托洛尔；扩张型心肌病；心力衰竭 [中图分类号] R541.6+1 [文献标识码] A [文章编号] 1674-4721（2017）02（a）-0150-03 [Abstract]Objective To explore the clinical effect of Benazepril combined with Metoprolol in the treatment of heart failure with dilated cardiomyopathy.Methods The clinical data of 60 patients were suffered from heart failure with dilated cardiomyopathy treated in Department of Cardiovascular Medicine，Houjie Hospital of Dongguan from January 2014 to January 2016 were analyzed.According to different therapeutic regimens，they were evenly divided into two groups，control group （Digitalis with Metoprolol，n=30） and observation group （Benazepril with Metoprolol，n=30）.The cardiac function and pulmonary function before and after therapy in heart failure patients with dilated cardiomyopathy were observed.The clinical effect of patients suffering from heart failure with dilated cardiomyopathy in the two groups was also observed.Results There was no significant difference in left atrial diameter，left ventricular end diastolic diameter，left ventricular ejection fraction，6 min walking distance，FEV1，FEV1/FVC，or FEV1% before treatment in the two groups （P0.05）.After therapy，all indexes in the two groups were both better than those before treatment，and these indexes in the observation group after therapy were better than those in the control group（P 　　1 资料与方法 1.1一般资料 选取2014年1月～2016年1月东莞市厚街医院心血管内科收治的扩张型心肌病心力衰竭患者60例临床资料进行分析，依据治疗方式不同进行分组，对照组30例，其中男19例，女11例；年龄38～79岁，平均（51.5±12.2）岁；病程5～21年，平均（7.3±4.1）年；心功能临床分级：Ⅱ级18例，Ⅲ级10例，Ⅳ级2例。观察组30例，其中男20例，女10例；年龄37～78岁，平均（50.9±11.1）岁；病程5～23年，平均（7.4±4.3）年；心功能临