超声剪切波弹性成像在桥本甲状腺炎临床诊断中价值.PDFVIP

J South Med Univ, 2017, 37(5): 683-686 doi 10.3969/j.issn. 1673-4254.2017.05.20 ·683 · 临床研究 超声剪切波弹性成像在桥本甲状腺炎临床诊断中的价值超声剪切波弹性成像在桥本甲状腺炎临床诊断中的价值 王 巍，郑海宁，王 琼，韩宜晓，叶庆桂，温朝阳 解放军总医院第一附属医院超声科，北京 100048 摘要：目的 探讨剪切波弹性成像技术（SWE）对桥本甲状腺炎（HT）不同分期的诊断价值。方法104例经临床确诊的HT 患者， 根据甲状腺功能状态分为HT 甲亢组（26 例）、HT 甲功正常组（29 例）、HT 亚临床甲减组（27 例）和HT 临床甲减组（22 例）。同期 选择健康志愿者作为健康对照组（50例）。利用SWE技术测量所有受检者甲状腺组织的杨氏模量值。采用Spearman相关分析法 分析甲状腺组织杨氏模量值与甲状腺峡部厚度、甲状腺微粒体抗体（TMAb）、甲状腺球蛋白抗体（TGAb）滴度的相关性。结果 健康对照组、HT 甲亢组、HT 甲功正常组、HT 亚临床甲减组、HT 临床甲减组甲状腺组织杨氏模量值呈递增趋势（P0.01）。HT 甲亢组剪切波弹性模量值低于HT 甲功正常组、HT 亚临床甲减组、HT 临床甲减组，差异均有统计学意义（P均0.05）。HT 甲功 正常组剪切波弹性模量值低于HT 亚临床甲减组、HT 临床甲减组，差异有统计学意义（P均0.05）。结论 剪切波弹性成像杨氏 模量值与桥本甲状腺炎不同分期患者临床表现有一定相关性，提示超声弹性成像对桥本甲状腺炎病程分期有一定的诊断价值。 关键词：桥本甲状腺炎；剪切波弹性成像；杨氏模量值；甲状腺激素类 Value of ultrasound shear wave elasticity imaging in diagnosis of Hashimotos thyroiditis WANG Wei, ZHENG Haining, WANG Qiong, HAN Yixiao, YE Qinggui, WEN Chaoyang Department of Ultrasound, First Affiliated Hospital of General Hospital of PLA, Beijing 100048, China Abstract: Objective To investigate the correlation between Youngs modulus of the thyroid tissue measured by in shear wave elastography (SWE) and the clinical manifestations of Hashimotos thyroiditis in different stages. Methods A total of 104 patients with the clinical diagnosis of Hashimotos thyroiditis were enrolled in this study, including 26 with hyperthyroidism, 29 with normal thyroid function, 27 with subclinical hypothyroidism, 22 with clinical hypothyroidism, with 50 healthy volunteers serving as the healthy control group. All the subjects underwent SWE to obtain the Youngs modulus value of the thyroid tissue. Univariate analysis of variance was used to compare the Youngs modulus among the groups, and Pearson correlation analysis was used to analyze the correlation between the Youngs modulus of the thyroid tissue and serum lev