人血清中游离氨基酸指纹图谱的初步研究.pdfVIP

Advances in Analytical Chemistry 分析化学进展, 2017, 7(1), 1-8 Published Online February 2017 in Hans. /journal/aac /10.12677/aac.2017.71001 A Preliminary Study on Free Amino Acid Fingerprint of Human Serum Hui Xu, Qiuhong Chen, Daoping Huang, Meiqing Su Guangxi Center for Analysis and Test Research, Nanning Guangxi th th th Received: Dec. 28 , 2016; accepted: Feb. 5 , 2017; published: Feb. 8 , 2017 Abstract Object: To establish free amino acid fingerprint of human serum. Method: The free amino acid of serum from the healthy persons was determined by the L-8900 automatic amino acid analyzer, and 15 major characteristic peaks of fingerprint were chosen as the common peak. Result: Free amino acid fingerprint of 12 batches of human serum was established. Conclusion: The fingerprint has preferably precision, repeatability and stability; it can be used as the theoretical basis of free amino acid fingerprint database of human serum. Keywords Human Serum, Free Amino Acid, Fingerprint 人血清中游离氨基酸指纹图谱的初步研究 徐 慧，陈秋虹，黄岛平，苏梅清 广西分析测试研究中心，广西 南宁 收稿日期：2016年12月28 日；录用日期：2017年2月5 日；发布日期：2017年2月8 日 摘 要 目的：建立人血清中游离氨基酸的指纹图谱。方法：采用L-8900全自动氨基酸分析仪测定健康人群血清 中的游离氨基酸，选择15个主要特征峰为指纹图谱共有峰。结果：建立了12批人血清样品的游离氨基酸 指纹图谱。结论：建立的指纹图谱有较好的精密度、重复性和稳定性，可作为人血清游离氨基酸指纹图 谱库的理论基础。 文章引用: 徐慧, 陈秋虹, 黄岛平, 苏梅清. 人血清中游离氨基酸指纹图谱的初步研究[J]. 分析化学进展, 2017, 7(1): 1-8. /10.12677/aac.2017.71001 徐慧 等 关键词 人血清，游离氨基酸，指纹图谱 Copyright © 2017 by authors and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Open Access 1. 引言 近年来，人们已逐渐认识到血液中氨基酸水平与身体各项机能的关系，且有大量的医学研究表明， 氨基酸含量的改变影响人体的生理功能并产生某些疾病，而某些疾病又影响氨基