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ARDS - Management By H P Shum Sept 2005 ARDS - Definition Bilateral acute lung infiltration Hypoxemia No clinical evidence of elevated left atrial pressure or PAWP =18mmHg Differentiated from Acute lung injury by PaO2/FiO2 300mmHg ARDS - pathophysiology Formation of protein-rich alveolar edema after damage to the integrity of the lung’s alveolar-capillary barrier Can be initiated by physical or chemical injury or by extensive activation of innate inflammatory responses ARDS - Causes Sepsis or SIRS Severe traumatic injury Massive transfusion Near drowning Smoke inhalation Drug overdose (commo
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