氟美松对急性肝损伤大鼠肝细胞FasFas配体表达和细胞凋亡的影响论文.docVIP

　　氟美松对急性肝损伤大鼠肝细胞FasFas配体表达和细胞凋亡的影响论文 周高速 张振书 王凡 林汉军 朱洁 【关键词】 氟美松 Effects of dexamethasone on Fas/Fas ligand expression and apoptosis of hepatocytes in rats ent by dexamethasone and to evaluate the potential role and mechanism in the pathogenesis of acute liver injury. METHODS: Expression of Fas/FasL protein and mRNA munohistochemistry and in situ hybridization, respectively. Apoptosis ined by terminal UTP nick end labelling (TUNEL) in rats during every phase of acute liver injury. RESULTS: Expression of Fas/FasL protein and mRNA inistration of dexamethasone suppressed apoptosis as RNA (P 0.0