从单光镊到阵列光镊.pdfVIP

22 6 Vol. 22 No. 6 2009 12 SpaceM edicine M edicalEngineering Dec. 2009 # 综 述# 从单光镊到阵列光镊* 王 欣, 李 勤, 胡晓明 (, 100081) : 本文介绍了近年来阵列光镊的发展状况,着重对利用声光偏转器衍射光学元件 间光调制器, 以及干涉垂直腔面发射激光器光纤微透镜阵列等形成阵列光镊的技术进行了简要介绍,并分析了每 种方式的原理特点以及系统的基本结构阵列光镊在颗粒操控方面具有明显优势,与微流控芯片制作 技术和MEMs技术相结合可进 一步小型化,成为便携式的颗粒分选仪器, 是进行 间生物学研究的 一个 很好的选择 : 阵列光镊;原理;基本结构; 颗粒操控; 颗粒分选; 间生物学 : TN249 : A : 1002-0837( 2009) 06-0464-05 F rom Sing le Op tica l Tw eezer to Op tica l Tw eezer A rray 1WANG Xin, LIQin, U Xiao-ming. SpaceM ed-i cine M edicalEngineering, 2009, 22(6): 464~ 468 Abstract: The paper introduced the recent development of optical tweezers array. The particlemanipulation system could be setup based on severalmethods, such as acousto-optics deflectors (AOD), diffractive optical elements (DOE), spatial lightmodulators (SLM ), interference technique, vertical cavity surface emitting la- ser (VCSEL), optical fibers and micro-lens arrays aswell. Theprinciple, specification and basic structure of each methodwere introduced and analyzed briefly. Taking the advantage of particle trapping, optical tweezers arraywas very useful formanipulation ofmicron size particles, such as cells. Combiningw ithmicrofluidics and MEMs fabrication, optical wt eezer array, the ultraminiature and portable particle sorting system, would be a good choice for space biological research. Key words: optical tweezer array; principle; setup; particlemanipulation; particle sorting; space biology Address reprint requests to: LIQ in. Department ofB iomedicalEngineering, School ofLife Science, Beijing Institute ofTechnology, Beijing 100081 [ 1] laser, VCSEL) Ashkin 1986 , , , , [2] :