羟基磷灰石纳米粒子的制备与表征.pdfVIP

Abstract Hydroxyapatite(HA), as the main inorganic component of the hard tissues in bones and teeth, is widely studied and has been used in clinical application to fill or restore damaged human calcified tissue because of its excellent bioactivity, biocompatibility and nontoxic ity. Increasing importance has been attached to preparation methods of nano-hydroxyapatite recently. But we still have many problems in study the preparation of hydroxyapatite. In this thsis, hydroxyapatite mamoparticles were synthesized by the reverse microemulsion method and the chemical precipitation method. TEM, XRD, IR were used to characterize the samples. The effect that was induced by the experiment parameter on the characterization of the nanoparticles has also been deeply researched. Hydroxyapatite nanoparticles that were synthesized by the neutralization with Ca(NO ) ·4H O and (NH ) HPO used as the reactants were in shape of 3 2 2 4 2 4 short rods or needles. Calcium phosphate mamowires could be obtained in the reverse microemulsions of ionic surfact ant , N-pentanol to cosurfactant , ammonia as a pH regulator prepared HA particles . The experimental results show that nano-HA particles increases with the ω value of particle size, reation temperature, aging time, cosurfactant increases, and with the reactant concentration, pH values increase in decrease . The average size was 40-50nm in length and 15-20nm in diameter.these are all close to the human bone’s structure. After calcined with 650 ℃, the length