冠心病伴左室收缩功能减退患者的心率变异性分析.pdfVIP

· 2038· 著 · 冠心病伴左室收缩功能减退患者的心率变异性分析 朱雅琴，黄震华，杨菊贤，汤政德 【摘要】 目的 探讨冠心病 (CAD)伴左室收缩功能减退患者的心率变异性 (HRV)的特征及临床价值。方法 将63例CAD患者分为A、B两组，A组为左室射血分数 (EF)50％的CAD患者30例，B组为EFi50％的CAD 患者33例；另选择健康对照者31例 (对照组)，进行24 h动态心电图监测，获得HRV各项时域指标并进行分析。结 果 A组、B组与健康对照组的SDNN、SDANN、SDNNI间差异均有显著性意义(P0．01)；A组和B组的SDNN、 SDANN间差异有显著性意义 (P0．01)，SDNNI间差异无显著性意义 (P0．05)。A组、B组与健康对照组的 rMSSD、PNN50问差异均无显著性意义 (P0、05)。结论 CAD尤其是CAD伴左室收缩功能减退患者的HRV明显降 低。 【关键词】 冠心病；左室收缩功能减退；心率变异性 【中图分类号】R 541．4 【文献标识码】A 【文章编号】1007—9572(2007)24—2038—02 Analysis of Cardiac Rhythm Variability in Paflen~ th Coronary Artery Disease Combined th Decrement of Left Ven- ． tricularSystofic~mlction ZHU Ya—qin，HUANG Zhen—hua，YANG Ju—xian，et a1．The Department ofCardiac and Pulmonary Function，the Ninth People s Hospital Affiliated to Medical College，Shanghai Jiaotong University，Shanghai 200011，China 【Abstract] Objective To investigate the characteristics and clinical value of cardiac rhythm variability(CRV)in patients with coronary artery disease(CAD)combined with decrement of left ventricular systolic function，Methods 24一hour dynamic ECG monitoring was carried out on 63 patients with CAD，who were divided into group A(n=30，EF50％)and group B(n：33，EFt50％)．31 normal subjects were chosen as control group．The various indexes of time domain in HRV were achieved and analyzed．Results Group A and group B were significantly different from the control group in SDNN， SDANN and SDNNI(P0，01)；There was significant difference in SDNN and SDANN between group A and group B(P 0．01)，but no significant difference was examined in SDNNI between them(P0．05)；Group A and group B were not signifi- candy different from the control group in rMSSD and PNN50(P0，05)． Conduslon HRV is obviously reduced in patients with CAD，especially in those who are comb i