临床生物样本库发展及其影响因素分析.pdfVIP

中华医学科研管理杂志 2017 年 4 月第 30 卷第 2 期 Chin J Med Sci Res Manage ,Apr. 2017 ,Vo l. 30 ,No. 2 • 85 • ·理论研讨· 临床生物样本库发展及其影响因素分析 李海燕倪明宇王晓民 E摘要】 目的 对临床生物样本库的发展及其影响因素进行分析，为临床生物样本库的建设发 展提供参考依据。方法 通过回顾北京重大疾病资源库建设发展过程，并结合国内外的相关文献报 道，对临床生物样本库的发展和影响因素进行定性分析。结果 随着生物样本库的迅速发展，随之带 来的是样本库的运行成本不断增大，也涌现出了各种问题，其可持续发展引起了越来越多的关注，受 共享应用、资金、人员队伍、信息化能力、战略需求和政策等方面影响。结论 临床生物样本库的运行 和可持续发展面临着越来越多的挑战。应该更多的是基于研究需求出发而进行临床样本库的设计和 建设，同时考虑利益相关者的利益需求，以提高样本库的效益，降低成本，确保样本库的可持续发展。 E关键词】 生物样本库; 可持续发展; 样本共享; 精准医学 基金项曰:北京市科委计划项目 (D13110700530000 ， D131100005313002) Analysis for the clinical biobanks sustainable development and influence factors Li Haiyαn ， Ni Mingyu , Wang Xiaomin. School 0/ Health Management and Education , Beijing 100069 ,P. R. China Corresρonding author: ，再Tang Xiaom巾， Email:xmwang@ [Abstract Objective Analysis the clinical biobanks sustainable development and influence , and give some advices for the development of clinical biobanks. Methods By review the development of Beijing Biobank of Clinical Resources , and combined with the related literature , we analysis the clinical biobanks sustainable development and influence. Results Wilh lhe rapid development of the biobank , its sustainable development has attracted more and more attention , and is influenced by sharing , funds , staff , information , strategies and policies. Conclusions The sustainable development of clini- cal biobanks is facing more and more challenges. For the sustainable development of clinical biobanks , the constructer should be focus on the requirement from the research , and pay attention to the inter ests of stakeholders. Key words Biobank; Sustainable development; Sample sharing; Precision medicine Fund program:Beijing Municipal Science Technology Commission(D13110700530000 ,D131100 005313002)