低度恶性子宫内膜间质肉瘤临床病理特征及误诊原因探析_仰晨.pdfVIP

15·68 · 仰 晨 低度恶性子宫内膜间质肉瘤临床病理特征及误诊原因探析 ?妇科肿瘤? 低度恶性子宫内膜间质肉瘤临床病理特征及误诊原因探析 仰 晨 The misdiagnosis and clinicopathologic features analysis of low － grade endometrial stro- mal sarcoma Yang Chen Department of Gynecology ，Affiliated Hospital of Nanjing Traditional Chinese Medicine University (Jiangsu Province Hospital of TCM)， Jiangsu Nanjing 210029 ，China． 【Abstract 】 Objective :To investigate the clinical and pathological features of low － grade endometrial stromal sar- coma (LGESS)，to improve the rate of the diagnosis of LGESS ，determine the operable range ，avoid the second － opera- tion． Methods :Two cases of LGESS were analyzed by means of reviewing the history records from April ，2010 to April 2011 in our hospital and connecting the correlative report． Ｒesults :The main clinical symptoms of LGESS were irregu- lar vaginal bleeding ，hypomenorrhea or postmenopausal ，hypogastric pain ，and occasionally touching a mass． The tumor cell resembled the endometrial stromal cell of proliferation phase on HE staining． There were a lot of blood vessels just like the spiral in the tumors． Two cases were positive for CD10 ，EＲ and PＲ by immunohistochemical findings． Conclu- sion :LGESS is very rare and easy to misdiagnosis ，the diagnosis relies mainly on histopathological and immunohisto- chemical findings． The prognosis of LGESS is better． It is necessary of diagnostic curettage before operating． In operat- ing if we doubt sarcoma ，we must rapid do histopathological examination． The curative effect of annexectomy and chemical therapy is better． 【Key words 】endometrial stromal sarcoma ;clinicopathologic features ;misdiagnosis Modern Oncology 2015 ，23 (11):1568 － 1570 【 】 : (LGESS) ， LGESS