第十九章 HIVAIDS病人抗病毒治疗6月后住院原因分析.docVIP

HIV/AIDS病人6月后住院原因分析 （南宁市第四人民医院 广西艾滋病临床治疗中心，南宁530023） 摘要：目的 了解广西地区HIV）感染者/艾滋病（AIDS）病人HIV/AIDS病人经高效联合抗反转录病毒治疗（HAART）超过6个月后所患疾病谱及对预后影响。 方法 回顾性分析2010年4月至2015年3月HAART超过6个月后HIV/AIDS病人住院的主要原因，将所患疾病分类为：HAART药物、急性感染性疾病、传染性肝病、结核病、其传染病、内科系统疾病、外科系统疾病、外伤、肿瘤、其疾病共10类，观察各类疾病的发生情况及对预后影响。 结果 共收集符合条件病人818例，男性占71.1%，年龄50岁占47.1%，CD+ T淋巴细胞计数200个/μL者占32.5%。各类疾病中，急性感染性疾病占19.6%，内科系统性疾病占17%，外科系统性疾病占13.9%，肿瘤占12.6%，HAART药物占8.3%，结核病占8.9%，传染性肝病占5.7%，其传染病占5%，外伤占3.7%，其疾病占5.4%。不良预后病人占10.9%，其中前三位为恶性肿瘤（47.2%）、急性感染（25.8%）和慢性肝病（9%）。 结论 本地区HIV/AIDS病人基础免疫低下多见，中长期HAART过程中感染性疾病风险较大，老年人比例高，合并病种多样，恶性肿瘤和感染是不良预后的主要原因。 关键词：病毒；高效联合抗反转录病毒治疗； 中图分类号：文献标志码：A 文章编号：1672-5662（201）0-0000-00 Analysis on hospitalization causes of HIV/AIDS patients after six-month’s HAART Wu Nianning，Peng Zhipeng，Huang Shaobiao (The Fourth People’s Hospital of Nanning，HIV/AIDS Clinical Treatment Center in Guangxi，Nanning, 530023，Guangxi, China) Supported by the National Key ST Special Projects (2012Z006) and by Scientific Research and Technology Development program of Nanning (201109047C) Abstract Objective To investigate the disease spectrum and influence on prognosis of HIV/AIDS patients under highly active antiretroviral therapy (HAART) over six months in Guangxi. Methods A retrospective analysis was made for the hospitalization causes of HIV/AIDS patients under HAART over six months during April 2010 to March 2015. The incidence of the diseases was observed including side effects of HAART, acute infectious diseases, infectious hepatitis, tuberculosis, other infectious diseases, internal system diseases, surgical system diseases, trauma, cancers and miscellaneous, and the influence on the prognosis was analyzed. Results A total of 818 conditioned cases were collected with 71.1% of males, 47.1% over the age of 50 years, and 32.5% whose CD4+T-lymphocyte count below 200 copies/μL. Among the various diseases described above, acute infectious diseases accounted for 19.6%, internal systemic diseases for 17%, surgical syst