泪腺腺样囊性癌的研究现状_王磊峰.pdfVIP

2007 6 25 6 　 ·477 · ·　　· 王磊峰　 　黑　砚　肖利华　 Currentresearchinadenoidcysticcarcinomaoflacrmialgland WangLeifeng.DepartmentofOphthalmology, SecondHospitalofBeijing rmedPolic,eBeijing100037, China 　　 bstrac　t denoidcysticcarcinoma(CC)isthemostcommonmalignantepithelialtumourofthelacrimalglandwiththe highestmalignantdegree.Recently, alotofnewcognitionshavebeenachievedaboutitshistopathologyformationsandclinical representation, henc,etherearesomedifferentconceptsinthetreamtentofCC.TheprognosisofCCdependsontheearly diagnosisandradicalsurgicalexcisionofthelesion.Radiotherapyandchemotherapyasadjunctsarenecessarybeforeorafter operation.Inaddition, advanceshavebeenacquiredinresearchofcytologyandmolecularbiologyaboutthebiologicalremarksof theoccurrenc,edistantmetastasesandneuralinvasionofCC.p53 andbc-l2 maybeinvolvedinoccurrenceofCC.The expressionofCD44 andMMPmaybecorrelatedwiththeprogressandrecurrenceoflacrmialglandtumors.TheSchwann scell differentiationmayaccounthistologicallyfortheneuralinvasionofCCoflacrmialgland.Currentresearchesin CCare reviewed.　　　　　　 　　Keywords　adenoidcysticcarcinoma; lacrmialgland;molecularbiology 　。 、、;, 、 、。 。 　 　 　 　;; 　R777.2　 　 100 3-0808 (2007 )06-0477-04 　　, ,,, [1] , 。 、。 2 , , 。, [2] 。 。 [3] 4.8%, 29% 。 ,, 。 。 ,,, , 、 [4] 。 、。 [3]