细针穿刺细胞学检查应用在甲状腺微小乳头状癌诊断中可行性分析.docVIP

细针穿刺细胞学检查应用在甲状腺微小乳头状癌诊断中可行性分析 　　[摘要]目的 探讨超声引导下细针穿刺细胞学检查（US-FNAC）在甲状腺微小乳头状癌（PTMC）诊断中的临床价值。方法 回顾性分析2014年3月～2016年10月我院门诊收治的行US-FNAC的95例PTMC患者（124个结节），比较US-FNAC诊断结果与术后病理及临床随访结果。结果 124个结节经US-FNAC诊断显示，恶性、可疑恶性、良性、不典型滤泡性病变、无效标本分别为78、23、13、2、8例；细胞学阴性20例，细胞学阳性104例；术后病理或随访显示，恶性101例，良性23例。US-FNAC诊断PTMC的敏感度为99.01%（100/101），特异度为82.61%（19/23），准确度为95.97%（119/124），阳性似然比5.69，阴性似然比0.01。结论 US-FNAC可应用于PTMC临床诊断中，具有较高的应用价值 [关键词]细针穿刺；细胞学检查；甲状腺微小乳头状癌；诊断 [中图分类号] R736.1 [文献标识码] A [文章编号] 1674-4721（2017）04（b）-0075-03 Feasibility analysis of fine-needle aspiration cytology applied in the diagnosis of papillary thyroid micro-carcinoma HE Jian-wo LUO Wen-jie LIANG Wei-bin FENG An-ye Department of Surgery，Enping Branch of Wuyi Traditional Chinese Medical Hospital of Jiangmen City in Guangdong Province，Jiangmen 529400，China [Abstract]Objective To investigate the clinical value of ultrasound-guided fine-needle aspiration cytology （US-FNAC） in the diagnosis of papillary thyroid micro-carcinoma （PTMC）.Methods The clinical data of 95 patients with PTMC （124 nodules） who underwent US-FNAC in our hospital from March 2014 to October 2016 were retrospectively analyzed.The diagnostic results of US-FNAC were compared with the results of postoperative pathology and clinical follow-up.Results US-FNAC showed that the numbers of malignant，suspected malignant，benign，atypical follicular lesions and ineffective specimens were 78，23，13，2 and 8 cases，respectively.There were 20 cases negative in cytology and 104 cases positive.The results of postoperative pathology or follow-up showed that there were 101 malignantcases and 23 benign cases.The sensitivity，specificity，accuracy，positive likelihood ratio and negative likelihood ratio of US-FNAC in the diagnosis of PTMC were 99.01%（100/101），82.61%（19/23），95.97%（119/124），5.69 and 0.01，respectively.Conclusion US-FNAC can be used in the clinical diagnosis of PTMC，which has higher application value. [Key words]Fine-needle aspiration；Cytology；Thyroid papillar