骨巨细胞瘤的生物行为评价研究进展.pdfVIP

i飞 cgjp回国室副医雪 .4517. 飞/躏梅毒草;襟捧都憾:影吉隆辙黯 ·新进展· 骨巨细胞瘤的生物行为评价研究进展 陶海波，飞勇，李码，丁莹莹，刘一帆 [摘要] 骨巨细胞瘤组织学及生物行为较复杂，侵袭力较强，具有较高的局部复发率，甚至发生远处转移如肺 转移。因此准确评价其生物行为对其临床诊疗尤为重妥，影像学、分子生物学II组织细胞学的发展为骨巨细胞瘤的生 物行为提供了全面评价体系。本文对骨巨细胞瘤生物行为评价的研究进展进行综述。 [关键词] 骨巨细胞瘤;分子生物学;组织细胞化学;综述 [中图分类号1 R 730. 262. 3 [文献标识码1 A doi: 10. 3969/j. issn. 1007 - 9572. 2015. 36. 025 陶海泼，飞勇，李鹤，等.骨巨细胞瘤的生物行为评价研究进展 [J] .中国全科医学， 2015 , 18 (36): 4517- 4520. [] Tao HB , Fei Y , Li K , et al. Research progress on the evaluatíon of biologícal behavior of gíant cell tumor of bone [J ] . Chinese General Practice , 2015 , 18 (36): 4517 -4520. Re能arch Progress on the Evaluation of Biological Behavior of Giant Cell Tumor of Bone TAO Hai - bo , FEI Yong , U Kun , et al. Department 0/ Radiology , the Third Æ庐liated Hospital 0/ Kunming Medical University (Yunnan Cancer Hospital lnstitω叶 ， Kunming 650118 , China [Abstra叫 The hist山gy and biological behavior of gíant cell tumor of bone (GCTB) is characterized by inherent complexity , strong aggressivity , high local recurrence rate and even the possibility of distant metastasis such as pulmonary metastasis. 币lerefore ， it is of great importance to provide precise evaluation of the biological behavior for the clinical diagnosis and treatment. The progresses in ima吕ing ， molecular biology and histocytology enable to provide a comprehensive evaluation system for the biological behavior of GCTB. ηle research progress in the evaluation of biological behavior of GCTB were reviewed in this paper. [ Key words 1 Giant cell tumor of bone; Molecular biology; Histocytochemistry; Review