2012 A New Norisoprenoid and Other Compounds from Fuzhuan Brick Tea 活性化合物可考虑投稿 Molecules.pdfVIP

Molecules 2012, 17, 3539-3546; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article A New Norisoprenoid and Other Compounds from Fuzhuan Brick Tea Zhen-Mei Luo 1,†, Tie-Jun Ling 1,†, Li-Xiang Li 1, Zheng-Zhu Zhang 1, Hong-Tao Zhu 2, Ying-Jun Zhang 2,* and Xiao-Chun Wan 1,* 1 Key Laboratory of Tea Biochemical and Biotechnology of Ministry of Education and Ministry of Agriculture, Anhui Agricultural University, Hefei 230036, China; E-Mails: yeziluozhenmei@126.com (Z.-M.L.); ling_tiejun@ (T.-J.L.) 2 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China † These authors contributed equally to this work. * Authors to whom correspondence should be addressed; E-Mails: zhangyj@ (Y.-J.Z.); xcwan@ (X.-C.W.); Tel.: +86-871-522-3235 (Y.-J.Z.); Fax: +86-871-515-0124 (Y.-J.Z.); Tel./Fax: +86-551-578-6765 (X.-C.W.). Received: 20 December 2011; in revised form: 8 March 2012 / Accepted: 14 March 2012 / Published: 19 March 2012 Abstract: Fuzhuan brick tea, a kind of dark tea consumed mainly in the border regions of Southwestern and Northwestern China since the 1860s, is produced from the leaves of Camellia sinensis var. sinensis by microbial fermentation. From this special fermented tea, a new norisoprenoid, 3R,9R-oxido-5-megastigmene, was isolated, together with α-linolenic acid, strictin, isovitexin, astragalin, (+)-catechin, (−)-epicatechin, (−)-epicatechin gallate, (+)-gallocatec