反复流产的联合治疗.pptVIP

* * Here is the left horn of a mouse uterus on day 13. The broken lined arrows indicate the haemorrhagic resorption (abortion) sites, whilst the solid line arrows point at the healthy embryos. The haemorrhagic spots in the picture denote reabsorbed embryos and illustrate the effects of the acoustic stress. 这是一只在妊娠13天的小鼠子宫的左角。虚线箭头所指示的是出血吸收（流产）点，同时实线箭头指示健康胚胎。 图中出血点表示再吸收胚胎并显示噪音对它的影响。 * * This slide shows the results of this comparison. Group 1 (grey bar) shows a baseline rate of 12.5% embryo resorption in the absence of acoustic stress. The rate increased to 44.1% in the presence of acoustic stress (green bar). When Duphaston? was given at 15 mg/kg in the presence of acoustic stress, this rate dropped to 25.4%. After 50 mg/kg of Duphaston?, even in the presence of stress, the resorption rate dropped to 18.7%. And most significant of all, when Duphaston? was given at 200 mg/kg in stressed animals, the resorption rate dropped to 5.8%, a figure below even the resorption rate in the group without stress (i.e. only baseline stress as a result of caging, feeding). 这张幻灯片比较了各组结果。 第1组（灰色柱）显示了无噪音刺激的情况下，胚胎吸收率的基值为12.5％。在伴噪音刺激的情况下，胚胎吸收率上升到44.1％（绿色柱）。 给伴有噪音刺激的小鼠应用达芙通? 15mg/kg时，该吸收率下降到25.4％，在给予达芙通50mg/kg时，即使有噪音刺激的存在，胚胎吸收率下降到18.7％。 最有意义的是，给予应激小鼠达芙通? 以200mg/kg时，胚胎吸收率下降到5.8％，比无应激组还要低。 * * In the Duphaston? group, the success rate of viable pregnancies was 85.4% compared to 80% in the control group - a statistically significant difference (p0.05). Similarly, the rate of abortion in the Duphaston? group was reduced by 27% versus the control group - 14.6% abortions compared to 20% - again a statistically significant result. 达芙通?治疗组存活妊娠的妊娠成功率为85.4%，对照组为80%-存在显著统计学意义 (p0.05)。同样，达芙通?治疗组的流产率比对照组下降了27%-14。6%对应与20%-同样具有显著统计学意义。 * * There was a significant difference seen in the patients who received Duphaston? compared with those who received standard treatment. In the Duphaston? group, 75.6% patients achieved term deliveries compared to only 66.7% in the control group. Only 7% of Duphasto