生长抑素与硫酸镁联合治疗重症急性胰腺炎临床观察.pdfVIP

第24卷第4期(第33页) 湖北民族学院学报·医学版 Vo1．24 No．4 P．33 2007年 Joum~of Hubei Institute for Nationalities·Medical Edition 2007 生长抑素与硫酸镁联合治疗重症急性胰腺炎 临床观察 刘勇帆，曾贱庚，黄国玲 吉安市中心人民医院普外科(江西吉安343000) 【摘要】目的 观察联合生长抑素和硫酸镁治疗重症急性胰腺炎(SAP)的疗效。方法 56例SAP患者随机分为联 合生长抑素与口服硫酸镁治疗组(n=29)和生长抑素组(n=27)，比较两组问入院时与治疗3 d及5 d后血、尿淀粉 酶及白细胞水平的差值的差异，比较两组腹痛、腹胀、发热、禁食、住院的时长及并发症发生率差异。结果 联合治 疗组治疗3 d和5 d后，血、尿淀粉酶及白细胞水平的下降幅度均高于生长抑素组(P0．05)。联合治疗组腹痛、腹 胀、发热、禁食、住院的时长和并发症发生率均小于生长抑素组(P0．05)。结论 联合生长抑素和口服硫酸镁治 疗SAP是一种疗效可靠、简便易行的方法，值得推广。 【关键词】硫酸镁；生长抑素；重症急性胰腺炎 【中图分类号】R657．5 1 【文献标识码】A 【文章编号】1008—8164(2007)04—0033—03 Combined Use of Sandostatin and Magnesium Sulfate in the Treatment of Severe Acute Pancreatitis LIU Yong—fan，ZENG Jian—geng，HUANG Guo—ling (Department ofGeneral Surgery，Ji an Center People S Hospital，Ji an 343000，China) 【Abstract】Objective To study the effects of combined use of sandostatin and magnesium sul— fate in the treatment of severe acute pancreatitis．Methods 56 cases were randomly divided into combined treatment group in which used magnesium sulfate and somatostatin(n=29)and SO— matostatin group(n=27)．The changes of urinary amylase，blood amylase，white blood cells frOm the hospital admission to the third day or the fifth day were observed．The length of stomachache，abdominal distension，fever，fasting，or stay in hospital and complications were recorded Results The decrease of urinarv amylase．blood amylase or white blood cells frOm the hospital admission to the third day or the fifth day in combined therapy group was higher than that in group of somatostatin，respectively(P0．05，respectively)．The length of stomach—