药品赋型剂的素材.ppt

人有了知识，就会具备各种分析能力， 明辨是非的能力。 所以我们要勤恳读书，广泛阅读， 古人说“书中自有黄金屋。 ”通过阅读科技书籍，我们能丰富知识， 培养逻辑思维能力； 通过阅读文学作品，我们能提高文学鉴赏水平， 培养文学情趣； 通过阅读报刊，我们能增长见识，扩大自己的知识面。 有许多书籍还能培养我们的道德情操， 给我们巨大的精神力量， 鼓舞我们前进。 * * RD Management Debrief Session Questions/Comments 1.????? Where it is noticed that an employee is having difficulty dealing with the changes, meet one-on-one to avoid the negativity cascading. 2.????? Will Etobicoke Signet (PE Stability Lab) be merged? If so, will they be on one site? 3.????? Who will provide input into which department a Supervisor will go to? Does the Supervisor have a vote? 4.????? Is Raw Material testing in scope with the Solid Dosage Re-organization? 5.????? All management should be informed/involved in the forthcoming changes well in advance. 6.????? Was there a contingency plan for the ‘reactions’ after the roll out? The ‘uncertainties’ with everyone’s future is causing a lot of anxiety at all levels. 7.????? Jeremy mentioned that Regulatory Affairs at Etobicoke is part of RD and made some RA announcements, but staff was unclear at the end of the meeting whether or not those were all of the RA changes. Are more changes coming? Can we communicate that RA is being addressed and timing of further changes for RA? 8.????? Will the Product Development Department at Etobicoke be divided? 9.????? Who will the groups report to (Bio Stability, Raw Material testing for Formulation Development and Preformulation Testing for Formulation Development, Demo batch testing for Tech. Transfer)? What group will they belong to? When will the changes take place? * * * Shanghai 2004 * NASONEX中赋型剂的定量 气相色谱（GC） 方法 柱子: G43 stationary phase, capillary column 0.53mm x 30m 检测器: FID 载流气体：Helium 进样器温度： 240 C 检测器温度：260 C Shanghai 2004 * NASONEX中赋型剂的定量 柱子温度: 时间(min) 温度(C) 速度(C/min) 0-10 40 10-31 250 10 31-46 250 Shanghai 2004 * NASONEX中赋型剂的定量 HPLC和GC的结果接近，但是HPLC需时要少得多（仅为GC的1/3时间) Shanghai 2004 * NASONEX中赋型剂的定量 氯苯甲烷铵的定量 功用：防腐剂 HPLC 方法 柱子：Spherisorb S3 CN 150mm x 4.6 mm, 3um 流动相：45%A