上海交通大学医学院 新华 儿童 儿童医学中心 儿科学 之 CA-MRSA-09.10.ppt

STAPHYLOCOCCUS staphyle - a bunch of grapes kokkus - berry 1928 所有葡萄球菌对青霉素敏感 1942 首次从病人分离耐青霉素的葡萄球菌 1950‘s医院内耐青霉素葡萄球菌大流行 头孢霉素、红霉素、万古霉素 1960 甲氧西林 耐青霉素酶 1961 首次在伦敦出现MRSA Methicillin-resistant Staphylococcus aureus (MRSA) difficult-to-treat infections multidrug-resistant SA or oxacillin-resistant SA (ORSA) resistant to a large group of antibiotics called the beta-lactams penicillins cephalosporins G+全球耐药状况 （2005-2006) MRSA MRSA infections in hospitals from 127,000 in 1999 to 278,000 in 2005 annual deaths increased from 11,000 to more than 17,000 at the same time M