核医学应用论文概要1.docVIP

目 录 Abstract 2 1前言 3 1.1选题背景 3 1.2核医学技术成像原理 3 2正电子发射断层成像技术(PET) 5 2.1PET成像机理 5 2.2PET工作原理 5 2.2.1晶体探测器功能及晶体材料 5 2.2.2数据采集、处理原理 7 2.2.3 PET 的图像重建 7 2.2.4 数据校正 7 2.3优缺点 8 2.4小结 8 3单光子发射计算机断层成像技术（SPECT） 9 3.1基本原理 9 3.2SPECT获得人体图像方法 10 3.2.1倾斜的扇形束投影 10 3.2.2求出完整的透射投影数据 11 3.2.3 重建图像的解析算法 12 3.3优缺点 13 3.4小结 13 4核医学成像技术在医学上的应用 13 4.1PET/CT 技术在肺癌诊断上的临床应用 13 4.1.1PET/CT技术应用方法 13 4.1.2 结果 14 4.2　PET/ CT应用于肿瘤学的优势 14 5结论与展望 15 致谢 16 参考文献 17 核医学成像技术核医学技术主要包括PET（正电子发射计算机断层扫描仪）和SPECT（单光子发射计算机断层扫描仪）两大检查技术，在分子影像学研究中占据着极其重要的地位，可对活体组织中的生理生化过程做出定量分析，如血流量、能量代谢、蛋白质合成、脂肪酸代谢、神经递质合成速度、受体密度及其与配体结合的选择性和动力学、蛋白质功能与基因表达等.用正电子发射体直接标记药物，能够对药物剂量、作用部位、可能发生的毒副作用等做出前瞻性判断，判断其代谢反应的类型及产物，观察药物与其他药物的相互作用、药物与营养物质的相互作用、药物与受体的作用、药物与酶的相互作用等，从而达到诊断和疗效判断目的.. NXiaojun Abstract: 　 The nuclear medicine member phantom technology mainly includes PET (positive electron launch computer fault scanner) and SPECT (single photon emission computer fault scanner) two major inspection technologies, is occupying the extremely important status in the molecular phantom study research, may make the quantitative analysis to the Living specimen Organizations physiological biochemistry process, like the blood stream quantity, the energy metabolism, the protein synthesis, fatty acid metabolism, the nerve hand over the nature resultant velocity, the acceptor density and with the ligand union selectivity and dynamics, the protein function and the gene expression and so on. With the positive electron emitter direct mark medicine, can the poisonous side effect which to the medicine dosage, the function spot, possibly occurs and so on make the forward-looking judgment, judges its metabolic reaction the type and the product, the observation medicine with the other medicine interaction, the medicine and the nutrients interaction, the medicine and acceptors function, the medicine and the enzyme interaction and so on, thus achieves the diagnosis and the curative effect judgment goal. Keywords: Nuclear medicine image formation; Positive e