人类与医学遗传学4、线粒体病.pptVIP

Mitochondrial Diseases 线粒体病 马龙 医学遗传学国家重点实验室 The structure of a mitochondria Oxidative phosphorylation and ATP synthesis occur on inner membranes The human mitochondria genome 13 proteins,, 22 transfer RNAs and two ribosomal RNAs Every 30 minutes a child is born who will develop a mitochondrial disease by age 10. At least 1 in 200 individuals in the general public have a mitochondrial DNA mutation that may lead to disease. Mitochondrial disease is a relatively newly diagnosed disease – first recognized in an adult in the 1960s and in the 1980s for pediatric onset cases. It is greatly under