（参考翻译）12.1Herpes Zoster－hk.pptVIP

Summary Diagnosis : Treatment: Clinical manifestations + Laboratory tests Self-care at home Antiviral drugs Pain relievers Systemic corticosteroids Cool compress Topical creams Eye drops * * Herpes Zoster 带状疱疹 Huang Kun Teaching Contents Definition Etiology Pathogenesis Clinical manifestations Diagnosis Differential diagnosis Treatment Definition Herpes Zoster is a viral infection 病毒感染 characterized by neuralgic pain 神经痛 and clustered vesicles 水泡丛生 situated 位于 unilaterally along the distribution of a sensory nerve 感觉神经. Etiology Varicella-Zoster Virus 水痘-带状疱疹病毒(VZV) Human herpes virus type 3 (HHV-3) Dorsal root ganglion Pathogenesis Varicella 水痘 Latent infection 潜伏感染 Herpes zoster 背根神经节 Pathogenesis The following may cause the VZV to become active： Aging 衰老 Stress 应激 Fatigue 疲劳 Diseases that affect the immune system Anticancer 抗癌的 and immunosuppression 免疫抑制 treatments Clinical Manifestations Typical manifestations Special manifestations Symptoms Lesions 损伤 Ophthalmic 眼 zoster Otic 耳 zoster postherpetic neuralgia 带状疱疹后遗神经痛(PHN) others Typical Manifestations—symptoms Prodrome 前驱症状: fever, headache, malaise 不适 sensations of burning pain, itching 瘙痒, hyperesthesia 感觉过敏 Pain: characteristic symptom 特征性症状 precedes 首发 or accompanies 伴随 the eruption of rash 皮疹 more severe in older patients usually subsides 平息 before the rash has healed Typical Manifestations－lesions erythema 红斑 and papules 丘疹 clustered vesicles 水泡丛生 pustules 脓疱 crusts 结痂 scar 瘢痕 12-24hs 3-4ds 7-10ds Typical Manifestations－lesions Distribution: unilateral (on one side of the body) dermatomal 皮区的 (an area of skin supplied by one spinal nerve 脊神经) Dermatome 皮节 Typical Manifestations－lesions Site of predilection 好发: Thoracic 胸部 dermatome 55%