17.2放射性核素治疗.pptVIP

Radioiodinated MIBG treatment of pheochromocytoma Pheochromocytoma Originate from chromaffin cells (嗜铬细胞） 90% located in adrenal medulla（肾上腺髓质） Producing and releasing catecholamines（儿茶酚胺） lead to paroxysmal（陈发性） or persistent hypertension and other symptoms. 10-20% of pheochromocytoma is malignancy（恶性） Diagnosis biochemical studies urinary and blood test ：catecholamines ， catecholamine metabolites Imaging techniques CT and MRI: highly sensitive , nonspecific MIBG scanning :highly specific , less sensitive Treatment The primary management of pheochro