三焦气化和能量代谢与痴呆病机的相关性探讨.pdf

辽宁中医杂志 2009年第 36卷第 4期 529 1, 2 1 1 1 , , , ( 1天津中医药大学第一附属医院针灸研究所分子生物学实验室, 天津 300193; 2天津中医药大学 2006级博士研究生, 天津 300193) : 随着老年人口的不断增加, 痴呆的发病率呈上升趋势目前, 痴呆的发病机制不甚明确, 中医认 五脏亏 虚, 气血津液运化失调, 痰湿瘀血浊毒内生 痴呆发生的主要病因,西医多数研究表明能量代谢与痴呆发生密切相关, 现就其发病机制作如下探讨 : 痴呆; 三焦气化; 线立体; 能量代谢 : R2418 : A : 1000- 1719( 2009) 04- 0529- 02 On the Basic Progress of Pathogenesis of Dementia to Analyse from Triple EnergizerQ iActivity and EnergyMetabolism 1, 2 1 1 1 WU Bangq i , L I Cunzhi , YU J ianchun , HAN J ingx ian ( 1Laboratory of M ol cular B iology, A cup unctur and M ox ibustion R s arch Institu t of T ianj in, Th F irst T aching H osp ital of T ianj in Univ rsity of Traditional Chin s M d icin , T ianj in 300193, China; 2T ianj in Univ rsity of Trad itional Chin s M dicin , T ianj in 300193, China ) Abstract:W ith the increasing of o u lation of old eo le, the morb ility of dem entia is ris ing. Nowadays, the athogenesis of dem entia is still unclearly, most of TCM theories shown that deficient ofW uZang, disorder of the function of q,i blood and body flu id leaded to the roduction of h legm atic hygrosis, stagnant b lood is them ain athogenesis of dementia, som e ex ermi en tal stud y suggested that energy m etabolism disorder is a mi ortant reason for dem entia, follow ing is the d iscussion for athogenesis of de m entia. K ey ords:Dem entia; Tri le Energizer Q iA ctivity; M itochondria; EnergyM etabolism 1 , , , , , , !∀ ##, , , , ∃; !: ∀ , , ∃; !: ∀ 2 , , , , , , , ∃, ; ,