颌间Ⅲ类矫形力动物模型的建立.pdfVIP

口腔医学2008年6月(第28卷第6期) Stomatology Vo1．垫!N0．鱼! ： 颌间Ⅲ类矫形力动物模型的建立 尹 康，徐 芸，李 松，李 煌，董宝财 [摘要] 目的 建立颌间Ⅲ类矫形力动物模型。方法 选用6只青春期雌性恒河猴为实验动物，实验组4只，配戴双阻板磁 力功能矫治器，对照组2只，不配戴矫治器。分别于3月、6月处死实验动物。结果 矫治器均配戴良好，实验动物殆位改变明 显，3月组平均殆位改变5．5 mm，6月组平均殆位改变6 mm。结论 采用双阻板磁力功能矫治器建立的颌间Ⅲ类矫形力动物 模型符合颌间Ⅲ类矫形力在力值和方向上的要求，能够较准确地模拟临床颌间Ⅲ类矫形的变化过程，可以作为研究颌间Ⅲ类 矫形理想的动物模型。 [关键词] 功能矫形；动物模型；双阻板磁力功能矫治器；恒河猴 [中图分类号] R783．5 [文献标识码] A [文章编号] 1003．9872(2008)06．0295．03 Establishment of animal model of intermaxiilary classⅢ fimctional orthopedic force YIN Kang，XU Yun，LISong，LIHuang，DONG Bao-cai．(Department ofOrthodontics，School ofStomotology，KumningMedical College，Kam— ming 650031，China) · Abstract： Objective To establish an animal model of the intermaxillary classⅢfunctional orthopedic force．Methods 6 pubertal rhesus monkeys were selected as the experimental animals，4 were treated with the twin-block magnetic app]iance(TMA)as experimental group，and 2 served as contro]group．The animals were killed separately after 3，6 months．Results The appliances on all animals were wom well，and there WaS obvious change on the occlusion position of the experimental animal，of which 5．5 mm changed for 3-month group and 6 mm for 6- month group．Condmion The magnitude and the direction of the force produced by twin-block magnetic appliance were competent to be印- plied as the classⅢfunctional orthopedic force and the ideal animal model for the study on the classⅢfunctional orthopedic treal／nent could be established through the application of TMA on the rhesus monkeys． Key words： functional orthopedies~animal model；twin-block magnetic app]iance~rhesus monkey Stomatology，2008，28(6)：295—297 安氏Ⅲ类错殆是临床上常见的严重影响颜面美 只(年龄3岁左右，体质量3．5 kg左右，云南省动物研 观的错殆畸形。临床上常用颌间Ⅲ类矫形力装置， 究所提供)牙列完整，牙周健康，无明显全身疾患。实 如颏兜、上颌前牵引装置、双阻板磁力矫治器等对早