刘舫教授应用加减川芎茶调散治疗原发性三叉神经痛临床视察.pdfVIP

提 要 目的：观察加减川芎茶调散治疗原发性三叉神经痛的临床疗效，为原发性三叉神 经痛（primary trigeminal neuralgia PTN）患者提供一种疗效确切，无毒副作用、 经济实用的治疗方法，并探讨其作用机制。 方法：将60例原发性三叉神经痛患者随机分为两组，治疗组给予加减川芎茶调 散，对照组给予卡马西平，两组均治疗30天为1个疗程，疗程结束后总结疗效。 结果：①临床疗效方面：治疗组总有效率90.0%，对照组总有效率66.67%，差异 有统计学意义（P0.05）；②疼痛积分方面：加减川芎茶调散能明显减少疼痛积分， 治疗后与治疗前比较有显著统计学差异（P0.01）。③中医症候疗效方面：治疗组总 有效率93.33%，对照组总有效率60.00%，差异有统计学意义（P0.05）；④症候评分 方面：加减川芎茶调散能明显减少症候评分，治疗后与治疗前比较有显著统计学差异 （P0.01）。 结论：加减川芎茶调散治疗PTN有较好疗效，可明显改善患者临床症状，提高生 活质量，且无毒副作用，有进一步深入研究、开发应用的价值。 关键词 原发性三叉神经痛；加减川芎茶调散；风邪外袭、瘀血阻络型；卡马西 平；临床研究 Clinical Observation on the Treatment of Primary Trigeminal Neuralgia with Jiajian Chuanxiongchatiaosan Decoction Used by Professor Liufang Speciality: Neurosurgery of integrated Traditional Chinese Medicine and Western Medicine Clinical Author: Bengyang Lv Tutor: Prof. Liufang Abstract Objective: Through observing the effect of Jiajian Chuanxiongcha tiaosan decoction in treating primary trigeminal neuralgia, to provides a definite effect, non-toxic side effects, economic and practical treatment method for primary trigeminal neuralgia (PTN) patients, and discusses their action mechanism. Methods: 60 patients with primary trigeminal neuralgia patients were randomly divided into two groups: treatment group and control group. the treatment group was treated with Jiajian Chuanxiongchatiaosan decoction, while the control group was treated with Carbamazepine, After the two groups treated for 30 days, effect was observed. Results: The total effective rate of clinic is 90.0% and 66.7% in the treatment group and in the control group respectively,There is statistically significant difference (P0.05).After treatment, Jiajian Chuanxiongchatiaosan decoction is significantly