烟草依赖的药物治疗尼古丁替代疗法.ppt

* 很多人会认为，烟草依赖只是一种个人习惯而已，其实，烟草依赖不只是一种个人习惯，而是一种明确界定的慢性病。 1998年世界卫生组织决议将烟草依赖作为一种疾病列入国际疾病分类(ICD-10,F17.2) ，确认烟草是目前对人类健康的最大威胁。 烟草依赖的特点是无法克制的尼古丁觅求冲动，以及强迫性地、连续地使用尼古丁，以体验其带来的欣快感和愉悦感，并避免可能产生的戒断症状，实质就是尼古丁成瘾。 Key Point Nicotine addiction is a cycle which begins with nicotine binding to receptors in the brain causing the release of dopamine which in turn results in feelings of pleasure and calmness. Background The distribution of nicotine is very rapid. It can reach the brain within 10 to 20 seconds after inhaling cigarette smoke.1 The binding of nicotine to its relevant receptors results in the