Analysis of Orthologous Retrovirus-Like Elements in the White-Footed Mouse, Peromyscus leucopus：（白足鼠同源Retrovirus-Like元素的分析,选择leucopus）.pdfVIP

J Mol Evol (1997) 44:74–80 © Springer-Verlag New York Inc. 1997 Analysis of Orthologous Retrovirus-Like Elements in the White-Footed Mouse, Peromyscus leucopus Ryan Sawby,* Holly A. Wichman Department of Biological Sciences, University of Idaho, Moscow, ID 83844, USA Received: 23 January 1996 / Accepted: 24 April 1996 Abstract. Three loci in the genome of the white- Introduction footed mouse, Peromyscus leucopus, were examined for the presence or absence of orthologous copies of the The retrotransposons found in the mammalian genome retrovirus-like element mys using polymerase chain re- are grouped by size and sequence similarity into families action. We examined these loci in 28 mice collected (Berg and Howe 1989). Some mammalian retroelement throughout the P. leucopus species range. Mys insertions families, such as the highly repetitive LINE-1 (L1) and were present in only one of the individuals examined at SINE families, are known to have been active both re- the mys-1 and mys-7 loci. Conversely, the mys-6 element cently (Batzer et al. 1991; Dombroski et al. 1991, 1993; was found in several individuals, but the presence of this Kazazian et al. 1988; Wallace et al. 1991) and over long element was limited to northern latitudes. Because the periods of evolutionary history (Burton et al. 1986; long terminal repeats (LTRs) of a given element are ex-