国产封堵器介入治疗动脉导管未闭临床应用及远期疗效观察.doc

国产封堵器介入治疗动脉导管未闭临床应用及远期疗效观察【摘要】 目的 总结国产封堵器经皮介入治疗动脉导管未闭的近远期疗效,评价国产封堵器治疗动脉导管未闭的临床价值。方法 2002年1月至2007年12月本院应用国产封堵器介入治疗动脉导管未闭患者93例,手术后分别行心电图、X线胸片和超声心动图随访。结果 91例成功,技术成功率97.8%。并发血红蛋白尿1例,重要并发症发生率为1.1%。随访X线胸片显示肺血较术前减少,心胸比例不同程度缩小。全组远期随访均保持优良生存,无因动脉导管未闭而再次接受治疗者。结论 国产封堵器介入治疗动脉导管未闭安全可靠、创伤小、并发症少、远期疗效优良,是治疗动脉导管未闭的理想方法。 【关键词】先天性心脏病;动脉导管未闭;介入治疗;远期疗效 Application of domestic occluder into transcatheter closure of patent ductus arteriosus and its bong trem results LI Bin,ZHANG Jian hua,GAO Hua,et al. Department of Thoracic and Cardiovascular Surgery, Affiliated the Second Hospital of University,Lanzhou,730030,China 【Abstract】 Objective To evaluate the immediate and long term clinical effectiveness of transcatheter patent ductus arteriosus(PDA)closure using domestic occluder.Methods From January 2002 to December 2007,93 patients underwent transcatheter PDA closure using domestic occluder,long term follow up results were made with electrocardiography,chest radiography and echocardiography.Results The technical success rate was 97.8%.Major complication was hemoglobinuria in 1 patient,and major complication rate was 1.1%.In 6 90(72.9±15.2)months follow up,patients with enlargement of left heart were found reduced obviously(P 2.2 随访结果 全组介入治疗成功91例,随访83例,随访率91.2%,失访8例。随访6~90个月,平均(72.9±15.2)个月。有残余分流者随诊1~3个月后残余分流消失。X线胸片示肺血较术前减少,心胸比例不同程度缩小。1年后TTE示左室舒张末径由(44.3±9.7)mm变为(38.5±5.5)mm(P 1