自体阔韧带替代人工硬脑膜修补后颅窝硬膜缺损临床分析.docVIP

自体阔韧带替代人工硬脑膜修补后颅窝硬膜缺损临床分析【摘要】 目的 探讨自体阔韧带替代人工硬脑膜修补后颅窝硬膜缺损的临床应用效果。方法 回顾分析2005~2009年我院后颅窝疾病的临床患者30例。结果 于后颅窝手术前即开始取下阔韧带,手术时间不超过10 min,最后均能达到水密、减张缝合后颅窝硬膜的目的。无一例患者有不良反应,均按期出院。结论 本文采用患者自体阔韧带替代人工硬脑膜,无任何排斥免疫反应,极大降低了治疗费用。其操作简单,安全性高,实用性强,应用此项技术极大降低患者的治疗费用,提高治疗效果,有效缓解家庭负担和社会负担,值得临床应用。 【关键词】人工硬脑膜修补;颅窝硬膜缺损 Broad ligament replacement with autologous patch of artificial dura mater of posterior cranial fossa dural defects in clinical analysis of AI Yan-ping,HE Xi-wu.Henan Province Xuchang Chinese medicine hospital,Xuchang 461000,China 【Abstract】 Objective To explore the broad ligament replacement with autologous patch of artificial dura mater of posterior cranial fossa dural defects in clinical application.Methods Retrospective analysis in 2005~2009 in our hospital clinical posterior fossa disease,30 patients.Results The posterior cranial fossa surgery began to remove the broad ligament before the surgery takes less than 10 min,finally able to achieve watertight,suture the posterior fossa subdural purposes.None of the patients had adverse reactions,are discharged from hospital on schedule.Conclusion In this paper,broad ligament replacement in patients with autologous artificial dura,without any rejection immune response,which greatly reduces the cost of treatment.Of its simple operation,high safety,practical,application of this technology greatly reduces the costs of treating patients,improve treatment,effectively ease family burdens and social burdens,it is worth clinical application. 【Key words】Artificial dura mater repair; Cranial fossa dural defect DOI:10.3760/cma.j.issn 1673-8799.2010.06.65 作者单位:461000河南省许昌市中医院(艾艳平); 青海省人民医院神经外科(贺喜武) 据资料统计有10%~30%的脑外科手术需要实施硬脑膜修补,尤其以颅底手术比例较高。硬脑膜是保护脑组织的一道重要屏障,创伤、肿瘤侵蚀及手术等均可造成硬脑膜缺损,目前国内外有超过40种硬脑膜替代物应用于临床,其中冻干同种硬脑膜因具有良好的组织相容性,并发症相对较少,移植效果较好,但是其来源较为困难、可见术后颅内感染的报道,因此理想的硬脑膜替代物仍有待进一步研究。本文对2005~2009年我院利用自体筋膜替代硬脑膜的30例患者进行回顾分析,总结如下。 1 资料与方法 1.1 一般资料 选取2005~2009年我院后颅窝疾病的临床患者30例,其中男19例,女11例;颅脑损伤15例,小脑出血10例,后颅窝肿瘤5例,均行开颅手术,硬膜减张