泻肺平喘合剂治疗喘憋性肺炎痰热闭肺证临床探究.pdfVIP

提 要 目的：从理论、临床两方面对泻肺平喘合剂治疗喘憋性肺炎痰热闭肺证的疗效进 行系统观察和研究，并探讨其作用机理,为小儿本病本证的医治寻求新方法、新途径。 方法：将符合西医毛细支气管和中医肺炎喘嗽痰热闭肺证诊断标准的 60 例患儿，随 机分为治疗组和对照组各 30 例。两组均在常规治疗的基础上，治疗组给予泻肺平喘 合剂灌肠，对照组给予小儿咳喘灵冲剂口服,七天为一疗程。七天后观察两组临床疗 效，同时进行对照比较。结果：临床研究显示,治疗组总有效率为96.7％，对照组总 有效率为 86.7％，治疗组疗效明显优于对照组（P＜0.05）。在改善发热、咳嗽、喉 间痰鸣、喘憋、肺部啰音、x 线胸片异常、T 细胞亚群等主要症状、体征、辅助检查 方面以及住院时间方面治疗组均优于对照组 （P＜0.05）。两组在改善鼻煽、精神异常、 小便异常方面比较P＞0.05，无差异。两组在改善紫绀、咽赤、口渴、大便异常方面 比较P＜0.05，有差异，治疗组优于对照组。两组在白细胞计数异常改善方面无差异 （P＞0.05）。同时治疗组疗效与小儿年龄、病情、病程有关（P＜0.05）：即年龄愈小 疗效越差，年龄愈大疗效越好；病情愈轻疗效越好，病情愈重疗效越差；病程愈短疗 效越好，病程愈长疗效越差。临床安全性指标研究结果表明：泻肺平喘合剂对于重要 脏器无毒副作用。结论：泻肺平喘合剂治疗喘憋性肺炎痰热闭肺证是安全有效的，值 得临床推广和应用。 关键词 喘憋性肺炎；泻肺平喘合剂；临床研究 Clinical Studies on Children Bronchiolitis Specialty: Respiratory Disease, Pediatrics Medicine of TCM Author:Liu ZiMei Tutor:Pro.Gao Shuying Abstract Objective:By observing and investigating the curative effect of Xie Fei Ping Chuan Mixture on treating the disease of phlegm-heat obstracting lungs of children Bronchio1itis and its mechanisation through theory and clinic.We try to find a new method and way which can treat the disease of phlegm-heat obstracting lungs of children Bronchio1itis .Methods ：According to the rule of stratified randomization, 60cases had been carefully chosen as study subjects according to the western medicines diagnostic criterion of childrens bronchiolitis and the TCM diagnostic criterion of accumulation of phlegm-heat syndrome of childrens bronchiolitis. According to the rule of randomization, all subjects were divided into two groups,the treatment group and control group,30 cases of each. Both groups were given the routine treatment, at the same time,The treatment group was given Xie Fei Ping Chuan Mixture enema.The control group was infused cough