温阳止泻合剂治疗2型糖尿病性腹泻的临床探究.pdfVIP

提 要 目的：观察温阳止泻合剂对2型糖尿病性腹泻病变相关因素的影响。通过患者治 疗前后的临床症状评分、血糖、糖化血红蛋白、血浆胃动素、血清胃泌素、生长抑素 等指标的检测，探讨其临床应用价值。方法：在基础降糖治疗的前提下，将60例临床 诊断为2型糖尿病性腹泻的患者随机分为两组，其中治疗组30例，给予温阳止泻合剂； 对照组30例，给予四神丸治疗，两组均以四周为一个疗程，观察两个疗程。结果：经 临床观察，治疗组在改善本病的症状，降低临床症状积分方面优于对照组（P0.05）； 在改善血糖、糖化血红蛋白、胃肠动力、植物神经功能等方面明显优于对照组 （P0.05）；并且在治疗过程中未发生不良反应。结论: 临床观察表明温阳止泻合剂 治疗2型糖尿病性腹泻，可明显改善患者的临床症状，降低血糖、糖化血红蛋白、改 善胃肠动力方面起到了积极作用，并且无明显不良反应，是一种预防和治疗2型糖尿 病性腹泻的有效方法，值得进一步研究并有一定的临床实用价值。 关键词 2型糖尿病；腹泻；温阳止泻合剂 Clinical Study on Treatment of The Diarrhea Caused by Type 2 Diabetes By Wenyang Zhixie Heji Speciality: Internal Medicine of TCM Author:Li zhihua Tutor: ProfessorGuo Baorong Abstract Objective:To investigate the effects of Wenyang Zhixie Heji on the diarrhea in type 2 diabetic patients related factors. By detecting the indexes that the patients cured the front and back, such as clinical symptom scores, blood glucose, glycosylated hemoglobin,serum gastrin,plasma motlilin and the somatostatin to explore its c1inical value. Methods:60 patients diagnosed type 2 Diabetes Mellitus with diarrhea were randomly classified into two groups.Under the basic premise of reducing the blood plasma glucose, 30 patients were treated with Wenyang Zhixie Heji in treated group,others were treated with pill of Sishen in control group.All of the groups were treated four 4 weeks as a course,taken for 2 courses. Results: Treatment group could improve the patients’clinical symptoms and signs, and the effects were better than control group (p0.05).In the sides of blood glucose, glycosylated hemoglobin, gastrointestinal function, autonomicnervousfunctionand so on， the effects of treatment group were better than control group (P0.05). And that there