益气活血汤治疗大脑后循环供血不足性眩晕的临床探究.pdfVIP

提 要 目的：通过应用导师经验方“益气活血汤”治疗大脑后循环供血不足性眩晕进行临 床疗效观察及分析评定，为大脑后循环供血不足性眩晕的中医研究及治疗提供新的思 路和方法。 方法:选取 80 例大脑后循环供血不足性眩晕患者随机分为益气活血汤组(40 例)和 氟桂利嗪组(40 例) ，两组均治疗 3 周，3 个月后随访。疗程结束后对两组的眩晕临床 总疗效、中医证侯积分、主要症状变化、颅脑基底动脉经颅多普勒（TCD ）、全血粘 度、纤维蛋白原进行对比观察，并在 3 个月随访时观察患者眩晕临床总疗效。 研究结果:治疗结束后，治疗组总有效率 92.50%，对照组总有效率 70.00%，两组 比较有显著差异(P ﹤0.01) 。在改善中医证侯积分、主要症状变化、颅脑基底动脉 TCD、 全血粘度、纤维蛋白原等方面，治疗组疗效亦优于对照组(P ﹤0.01 或 P ﹤0.05) 。3 个 月随访时两组患者眩晕临床总疗效比较，治疗组疗效亦优于对照组（P0.01 ）。 结论: 益气活血汤加阿司匹林及氟桂利嗪无论在改善大脑后循环供血不足性眩 晕患者临床症状还是在改善血流动力学、血液流变学指标方面均有较好疗效，且远期 疗效好，是治疗大脑后循环供血不足性眩晕安全可靠的有效药物，值得进一步对其作 用机制加以探讨。 关键词：大脑后循环供血不足；眩晕；中风病先兆症；益气活血汤；临床研究 The Clinical Research of YiQiHuoXue Prescription Treating Cerebral Posterior Circulation Insufficiency Vertigo Specialty：the Clinical Discipline of Traditional Chinese and Western Integrative Medicine Author: Wangqin Tutor：Pro. Youke Abstract Objective：Based on years of experience that my tutor has gained in treating cerebral posterior circulation insufficiency vertigo. To observe the therapeutic effect of YiQiHuoXue decoction on the patients suffering from cerebral posterior circulation insufficiency vertigo and explore the mechanism，so as to find new ideas and effective prescriptions. Methods:In this thesis,80 patients with cerebral posterior circulation insufficiency vertigo were randomly divided into thetreatment group(YiQiHuoXue decoction –group ，40 cases)and control group(Flunarizine HCI(Sibelium)-group ，40 cases).Both were treated for 3 weeks,then being compared with their Symptoms , physical signs brain TCD and blood viscosity and Fb before and after treatment. Results:The statistic analysis revealed that the treatment group display total effective 92.50%, while t