礞石滚痰丸加减方治疗痰热郁结型抑郁症的临床探究.pdfVIP

提 要 目的：本课题旨在运用中医理论结合现代研究方法，在系统回顾相关文献和总结 临床经验的基础上，探讨礞石滚痰丸加减方用于治疗痰热郁结型抑郁症的临床疗效和 机理，寻求治疗抑郁症的新思路。方法：本课题共选择符合《中国精神障碍分类与诊 断标准第三版》（CCMD-Ⅲ）中抑郁发作诊断标准和中医郁病痰热郁结辨证标准的 60 例病人，随机分为礞石滚痰丸加减方治疗组（30例）和黛力新对照组（30例）。结果： 治疗组总有效率73.33%，较对照组（黛力新组）76.67%，无显著性差异（P＞0.05）。 表明礞石滚痰丸加减方与黛力新疗效相当。在改善中医证候方面，两组临床总疗效有 显著性差异（P＜0.05），治疗组明显优于对照组，提示礞石滚痰丸加减方治疗组在改 善患者中医证候方面明显优于对照组。结论：礞石滚痰丸加减方可明显降低患者汉密 尔顿抑郁量表（HAMD），抑郁自评量表（SDS）分值，并有效改善中医证候。礞石滚痰 丸加减方具有化痰清热、解郁安神的作用，对痰热郁结型抑郁症具有良好的治疗效果。 关键词 抑郁症；痰热郁结；礞石滚痰丸加减方；临床研究 Clinical Research of Mengshiguntan Pill Jiajian Fang in Treating Depression Speciality： Internal Medicine of TCM Author ： Shi Shuangshuang Tutor： Pro. Hu-Zhiqiang Abstract Objective ：Based on systematically review of past dynasties’ documentation and tutors many years of clinical experiences ，this study focus on the clinical effects and mechanism of Mengshiguntan Pill Jiajian Fang ，and is aimed at finding a new view to treat depression，with the way of combined the Chinese medicine theory and modern research method. Methods ：60 patients who were diagnosed as depression according to the diagnostic standard of depression of CCMD-Ⅲwith TCM syndrome of binding depression of phlegm-heat and qi，were randomly divided into two groups ：Mengshiguntan Pill Jiajian Fang treating group ，which group were treat with Mengshiguntan Pill Jiajian Fang decoction to clear phlegm and heat（30 cases ）and Deanxit pills control group， which took Deanxit pills （30 cases ）. Results ：The clinical result showed that total effective rate was 73.33% in treating group and 76.67% in control group. These results prov