祛痰活血颗粒剂治疗冠心病心绞痛痰瘀互结型的临床探究.pdfVIP

提 要 目的：本研究旨在观察祛痰活血颗粒剂治疗冠心病心绞痛痰瘀互结型的临床疗效 并探讨其作用机理。 方法：临床研究中，将痰瘀互结型冠心病心绞痛的患者 60 例随机分为两组，对 照组30例，给予常规西药治疗；治疗组30例，在常规西药治疗的基础上给予祛痰活 血颗粒剂治疗。4 周后，观察治疗前后临床症状、心电图 ST-T 改变、化验室检查指 标等，并进行统计学分析。 结果：1.两组对冠心病心绞痛症状缓解及心电图改善均有显著的疗效，治疗组的 疗效要优于对照组。2.两组在改善中医症状方面，治疗组明显优于对照组。3.治疗后 两组血脂总胆固醇及低密度脂蛋白、C-反应蛋白(CRP)、血流变水平均有下降，且治 疗组下降更明显。 结论：祛痰活血颗粒剂是临床上治疗痰瘀互结型冠心病心绞痛的一个安全、疗效 确切的中药复方制剂，并因中药的毒副作用小及整体调治，在治疗冠心病上有着广阔 的前景和其他药物无法比拟的优越性。 关键词 冠心病心绞痛；痰瘀互结型；祛痰活血颗粒剂；中医药治疗 Clinical Research of the Therapeutic Effects of QuTanHuoXue granule on angina pectoris with intermingled phlegm and blood stasis Speciality：Internal Medicine of Traditional Chinese Medicine Author ：Qu Hong Tutor：Meng Zhaoyang Abstract Objective : Observation the clinical effect on treating angina of Tanyuhujie type of syndrome to explore it’s mechanism. Methods: 60 patients with angina of Tanyuhujie type of syndrome were randomly selected and divided into two groups, 30 patients in treatment group and 30 patients in control group.One group was treated with QutanHuoxue granule and general western medicine,the other one with general western medicine.After 4 weeks were observed the treatment of clinical symptoms,the ST-T changes of ECG, laboratory examination and analyzed statistically.Results: 1. Two pairs of Coronary Heart Disease to alleviate symptoms and ECG were significantly improved efficacy, the efficacy of the treatment group is superior to the control group 2.Chinese medicine in improving symptoms, treatment group was significantly better than the control group.3.After treatment, total cholesterol and LDL lipids, C-reactive p