特发性血小板减少性紫癜部分脾动脉栓塞术的临床疗效分析.pdfVIP

现代医药卫生2008年24卷第6期 特发性血小板减少性紫癜部分脾动脉栓塞术的临床疗效分析 徐城林 (攀枝花市第二人民医院，四；11攀枝花617068) 【摘要】目的：探讨部分脾动脉栓塞术治疗特发性血小板减少性紫癜的临床疗效。方法：对21例特发性血小板减少性紫癜患者在 数字减影血管造影(digital subtraction angiography，DSA)下行超选择性脾动脉栓塞术治疗。结果：21例患者均于术后3~lIIId,板开始 上升，7～14天达高峰，总有效率85．7％，术前、术后血小板计数差异有显著性(P0．O1)。结论：部分脾动脉栓塞术治疗特发性血小板减 少性紫癜疗效明显．并发症少，值得推广。 【关键词】特发性血小板减少性紫癜；脾动脉栓塞；疗效 文章编号：1009—5519(2008)06—0808—02 中图分类号：R5 文献标识码：A Evaluation 0f the clinical effect 0f the partial splenic artery embolism in idiopathic thrombocytopenic purpura XUCheng-lin (The Second People Hospitd ofPartzhihua，Sichuan 617068，China) 【Abstract]Objectlve：To evaluate the clinical effect of the partial splenic artery embolism in idiopathic thrombocytopenic purpura (ITP)．Methods：Twenty-one patients who were diagnosed as ITP were done by selective splenic artery embolism in di#tM subtraction angiography．Results：All of their platelet began to rise on the postoperative third day and reached the top during the seventh to four— teenth day．The total effective rate accounted for 85．7％．The platelet count difference was significant before and after treatment O．01)． Conclusion：It is showed that partial splenic artery embolism therapy is significant to ITP．Its complication is few．So it is worthy to be popularized． 【Key words]Idiopathic thrombocytopenie purpura；Splenic artery embohsm；Effect 特发性血小板减少性紫癜 f idiopathic or immune thrombo． 70％为佳。拔管后，加压包扎穿刺点，术后常规予以抗生素预防 eytoponie purpura．ITP)具有反复发作的特点．治疗方法虽然很 感染．出现发热、脾区疼痛、恶心、呕吐等栓塞综合征时予以对 多，但疗效不太理想。Roberto等『】1认为脾切除可用于治疗复发 症治疗。 性、难治性患者。但因脾切除手术创伤大．往往伴有机体免疫功 1．3．2 观察指标：(1)治疗后出血症状、体征变化；(2)治疗后血 能下降，易并发感染，患者常不易接受。我院自2001年4月～2007 小板计数．治疗开始后2周内每天抽肘静脉血验测血小板计数， 年6月共收治21例难治性ITP患者采用部分脾动脉栓塞治疗．取