血脂康胶囊对冠心病血脂达标患者血脂水平的控制探究.pdf

提 要 目的：观察血脂康胶囊对冠心病合并高脂血症患者达标血脂水平维持的临床疗 效，以期为治疗本病提供参考依据，并初步探讨血脂康胶囊治疗本类患者的优势和可 行性，以期为进一步改良及推广此法打下基础。 方法：随机选择冠心病伴高脂血症(治疗后血脂水平达标)患者 60 例，分为血脂 康组（20 例）、辛伐他汀组（20 例）和基础治疗组（20例），在继续冠心病基础治疗 的前提下，经药物洗脱期（2周）后，分别予以血脂康胶囊、辛伐他汀片和空白对照 治疗，并于2周、4周、6周末观察疗效。 结果：冠心病的基础治疗加血脂康胶囊抗心绞痛作用更明显（P＜0.05）；对冠心 病患者达标血脂水平维持的结果表明：基础治疗组在停用调脂药2周内血脂水平可保 持正常（P＞0.05），而停用调脂药物 4周后血脂水平不再达标（P＜0.05），血脂出现 反弹性升高；血脂康胶囊治疗量口服能够维持达标血脂水平的稳定（P＞0.05）；口 服治疗量血脂康胶囊与口服小剂量辛伐他汀片均能维持达标血脂 （TC、LDL-C、HDL-C） 水平稳定（P＞0.05）；而血脂康胶囊更能有效降低TG（P＜0.05）。 结论：口服治疗量血脂康胶囊能稳定冠心病伴高脂血症患者达标血脂水平，抗心 绞痛；与西药辛伐他汀片疗效相比，血脂康胶囊能更有效降低TG。 关键词 冠心病伴高脂血症；血脂康胶囊；临床研究；中医药治疗 Clinical Study on Maintaining The Lipid Level Reached The Standard In Patients With CHD With Xue Zhi Kang Capsule Speciality: Internal Medicine of Traditional Chinese Medicine Author: Liu Jin Bo Tutor: Pro. Su Wen Ge Abstract Objective: To investigate the clinical effect of maintaining the lipid level reached the standard in patients with CHD and Hyperlipidemia with xue zhi kang capsule.To provide a reference for treatment of this dissease.To explore the advantages and feasibility of treatment of this dissease with xue zhi kang capsule and western medicine treating idiopathic nephrotic syndrome and lay the foundation for further improvement. Methods: Method 60 Cases of premature beat of CHD and Hyperlipidemia ( the lipid level reached the standard after treatment ),and divided into xuezhikang group(20 cases) , simvastatin group(20 cases) and control group(20 cases). At the Premise of continueing the basic treatment of CHD. After a period of drug-eluting(two weeks),Be treated with xuezhikang capsule , simvastatin tablets and control for 2,4 and 6 weeks,then to observe the curative effect. Result: Basic treatment of CHD plus Xuezhikang capsul