行气利水方联合顺铂腹腔灌注治疗癌性腹水的疗效视察.pdfVIP

提 要 目的：针对消化系统肿瘤易出现癌性腹水的特点，通过临床研究行气利水方对于 消化系统肿瘤脾虚水泛型癌性腹水患者的疗效，旨在对消化系统癌性腹水患者的中西 医结合治疗做一个初步探讨，为优化中晚期癌性腹水的中医治疗方案提供临床研究资 料。方法：将 48 例符合纳入标准的脾虚水泛型癌性腹水患者随机分组治疗，其中观 察组（行气利水方加腹腔灌注顺铂）24 例，对照组（腹腔灌注顺铂）24 例，疗程为 4 周，观察两组患者治疗前后腹水疗效、中医证候积分、生活质量情况、血常规、肝 肾功及免疫指标等情况。结果：两组患者在腹水缓解稳定率、中医证候改善情况、多 项临床症状疗效、血常规、肝肾功及免疫方面，观察组明显优于对照组（P0 ．05 ）。 结论：中药行气利水方配合顺铂腹腔内化疗，治疗脾虚水泛型癌性腹水，与单纯西医 腹腔内化疗对比，可以提高患者的生活质量，改善患者的临床症状，此临床研究丰富 了消化系统脾虚水泛型癌性腹水的治疗，肯定了行气利水方的疗效。 关键词 癌性腹水；行气利水方；腹腔内化疗；临床研究 The Evaluation of Xing Qi Li Shui Fang Jointing Cisplatin Treating Malignant Ascites Specialty：Internal Medicine of Traditional Chinese Medicine Author ：Dong Wei Tutor：Professor Qi Yuanfu Abstract Objective: Malignant ascites is one of the important features of digestive system tumors ． Through the clinical observation of effectiveness of Xing Qi Li Shui Fang (XQF) for digestive system tumors intermingled diffussive water due to deficiency of spleen in patients with malignant ascites, we make a preliminary discussion about the tradiditional chinese medicine and western medicine treatment for the patients with malignant ascites, providing clinical research data to optimize the TCM treatment of medium-term and advanced malignant ascites ． Methods: 48 malignant ascites patients of intermingled diffussive water due to deficiency of spleen were divided randomly into two groups ． 24 patients in the observation group were administered with XQF and intraperitoneal perfusion with cisplatin, 24 patients in the control group with perfusion alone ． Objective effects and the changes of subjective symptoms were studied during and after sixty days of treatment ．Results: After two periods of treatment, the subjective symptoms 、KPS 、body weights 、immune parameters were all sig