除湿消疣汤加减治疗未成熟型疣状胃炎（湿热瘀结型）的临床探究.pdfVIP

提 要 目的：观察除湿消疣汤加减治疗未成熟型疣状胃炎(unmature verrucosa gastritis，UMVG)，中医辨证为湿热瘀结型的临床疗效，并从理论和临床研究两个方 面探讨除湿消疣汤治疗未成熟型VG的机制。方法：临床选择符合纳入标准的未成熟型 VG患者60例，随机分为两组，治疗组（30例）给予除湿消疣汤加减，对照组（30例） 给予增生平片，两组均以4周为一疗程，连服两个疗程，观察两组的临床疗效。结果： 临床研究显示，治疗组中医证候痊愈率+显效率为76.67％，胃镜疗效痊愈率+显效率 为66.67％，Hp清除率为78.26％；对照组中医证候痊愈率+显效率为33.33％，胃镜疗 效痊愈率+显效率为23.33％，Hp清除率为33.75％。两组疗效对比，均有非常显著性 差异（P0.01）。治疗组能明显消除或改善胃脘隐痛、痞闷、口苦口臭等症状，其疗 效优于对照组。结论：除湿消疣汤是治疗湿热瘀结型未成熟型疣状胃炎的有效方剂， 其作用机理可能与杀灭幽门螺杆菌（Hp），抗变态反应和调节机体免疫，改善微循环， 抗炎、促进粘膜修复等作用有关。 关键词 除湿消疣汤；未成熟型疣状胃炎；湿热瘀结型；临床研究 Clinical Study ofTreatingUnmatureVerrucosa Gastritis With Clinical Study ofTreatingUnmatureVerrucosa Gastritis With CClliinniiccaallSSttuuddyyooffTTrreeaattiinnggUUnnmmaattuurreeVVeerrrruuccoossaa GGaassttrriittiiss WWiitthh Chu--Shi-xiao-you-tang Chu--Shi-xiao-you-tang CChhuuSShhii--xxiiaaoo--yyoouu--ttaanngg Specialty Specialty SSppeecciiaallttyy GastroenterologyInternalMedicine ofTCM. ： Author Author AAuutthhoorr： ZhaoYan Tutor Tutor TTuuttoorr：ProfessorLu Guangchao Abstract Abstract AAbbssttrraacctt Objective Objective OObbjjeeccttiivvee：To observe the effect of Chu-Shi-xiao-you-tang (CSXYT) Decoction on Unmature Verrucosa Gastritis (UMVG) of damp-heat combined with blood stasis and Methods Methods explore the mechanism of it. MMeetthhooddss：60 patients with UMVG were divided into two groups at random:the treatment group and the control group.The treatment group was given CSXYT Decoction and the control group was given Zeng-Sheng-ping (ZSP) tablets.Symptoms and signs of each group were observed before and after the