除疣汤联合穴位埋线治疗扁平疣的临床观察和对T细胞亚群的影响.pdfVIP

提 要 目的：观察除疣汤联合穴位埋线治疗扁平疣热蕴络瘀证的临床疗效，并检测患者 治疗前后外周 T 淋巴细胞亚群的水平，以探讨除疣汤联合穴位埋线治疗扁平疣的作用 机理。 方法：将 60 例患者随机分为两组，治疗组予除疣汤内服外用，配合穴位埋线； 对照组予除疣汤内服外用。两组均外用重组人干扰素α-2b 凝胶﹙尤靖安﹚。6 个疗 程后判定疗效,并检测患者治疗前后外周 T 淋巴细胞亚群的水平。 结果：治疗组和对照组的痊愈率分别为 70.00% 和 50.00%，无统计学意义（P＞ + 0.05），总有效率分别为93.33%和73.33%，差异显著(P＜0.05）。治疗后，两组的CD4 、 + + + CD4 /CD8 比值较疗前升高，CD8水平降低，但两组仍有显著差异（P＜0.01）。 结论：除疣汤配合穴位埋线和单用除疣汤治疗扁平疣均有较好的临床疗效，但治 疗组优于对照组(P＜0.05）。作用机理可能为调节患者的细胞免疫功能。 关键词 扁平疣；除疣汤；穴位埋线；T 淋巴细胞亚群 The clinical observation on treatment of verruca plana with ChuYouDecoction joined catgut-embedding and its effect to T lymphocyte subsets Speciality：Dermatology ，Surgery of TCM Author ：Bi Yunpeng Tutor：Professor Song Yeqiang Abstract Objective: To observe the clinical efficacy of ChuYouDecoction joined catgut-embe- dding in treatment of verruca plana blood stasis，and study the level of peripheral blood T lymphocyte subsets in patients before and after treatment,explore its therapeutic mechanism. Methods: 60 patients were randomly divided into 2 groups. The cure group, ChuYouDecoction was for oral and topical use, joined catgut-embedding; the control group, ChuYouDecoction was also for oral and topical use. Recombinant human interferon α-2b gel (You Jingan) was for all patients. After six courses, observe the clinical efficacy, and study the level of peripheral blood T lymphocyte subsets in all patientsbefore and after treatment. Results: The cure rate of the cure group and the control group was 70% and 50%,but it had no statistical significance (P 0