围术期奥美拉唑预防高血压脑出血_重型颅脑损伤后急性应激性溃疡的疗效观察.pdfVIP

2010 10 26 10 J Cli A esthesiol, October 2010, Vol. 26, No. 10 863 范丹 蒋蓉 谢先丰 许婷 兰志勋 ! pH ( SU) 30 , , A 40 mg, B C 40 mg800 mg, ( T ) 2 h(T ) ( T ) ICU 0 1 2 1 ( T ) 2 (T ) 3 ( T ) pH 3 4 5 ( Cor) (ACTH) A pH T ~ T B 1 3 C ( P 005) , A ACTH Cor T ~ T B C ( P 005) , A 1 3 SU, B 1 C 2 SU SU ! ; ; ; Effect of prophylacticomeprazole on stress ulcerafter hypertensive intracerebral hemorrhage and severe brain injury FAN Da , JIANG Ro g, XIE Xia f e g, et al . Departme t of A est hesiology , Sichua Provi cial Peoples Hospital , Che gdu 610072, Chi a Abstract! Objective T o i vestigate the effect of omeprazole o gastric fluid pH value a d acute stress ulcer after hyperte sive i tracerebral hemorrhage or severe brai i jury .Methods Thirty hyperte sive i t racerebral hemorrhage or severe brai i jury patie ts u dergoi g cra iotom y w ere ra domized divided i to three groups A(received 40 mg omeprazole i trave ously before i ductio ) , B ( 40 mg omeprazole at the e d of surgery) a d C( 800 mg Cimetidi at the e d of surgery) . Gastric fluid pH value a d red blood cell cou t, occult blood test, plasma corticosteroid ( Cor ) a d adre ocorticotroph ( ACTH) w ere detected before a est hesia( T ) , 2 hr after i cisio ( T ) , at the 0 1 e d of operat io ( T ) , 1, 2, a d 3 postoperat ive day( T , T , T ) . Results The gastric fluid pH 2 3 4 5 value at T , T , a d T i group A were higher tha that of group B a d C. ( P 005) The plasma 1 2 3 co ce trat io