失眠6（Insomnia 6）.doc

失眠6（Insomnia 6） Health care therapy The depth of investigation found that Western occupation managers generally have a sleep management consciousness, in their view, sleep is the inalienable natural rights, spend less time than others than others sleep a good mental state is very important. In their sleep management plan, take care to help sleep is essential. The current use of sleeping health care products all over the world is the melatonin, also known as melatonin and melatonin. Depth analysis: Regulation of melatonin on sleep and its relationship with amino acid transmitters in brain Authors: Wang Fang, Li Jingcai, Xu Feng, He Yu, Tang Chao Setting: Department of time biology, Shenyang Pharmaceutical University, Shenyang 110016, China Keywords: Melatonin; sleep; circadian rhythm; GABA; glutamic acid Abstract Objective: To study the effect of melatonin on sleep and circadian rhythm and its relationship with amino acid transmitters in brain. Methods: the effect of melatonin on the sleep and circadian rhythm of mice was studied by righting reflex. The effect of melatonin on GABA (GABA) and glutamic acid (Glu) content in different brain areas of mice was determined by paper electrophoresis double wavelength scanning method. Results: melatonin can obviously promote the sleep of mice, and its potency depends on the time of administration. Melatonin can increase the GABA content in the hypothalamus of mice. But it has no obvious influence on the level of glutamic acid. Conclusion: the effect of melatonin on sleep may be related to the increase of GABA content in the hypothalamus of mice. Melatonin (melatonin, MT) mainly secreted by the pineal gland, which has a variety of biological activity. Since its synthetic and health food market, there has been a great upsurge of melatonin research both at home and abroad. Among the many functions of melatonin, the induction of natural physiological sleep and the correction of disturbed sleep wake rhythms are particularly attract