伽玛刀治疗脑胶质瘤（Gamma knife radiosurgery for brain gliomas）.docVIP

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伽玛刀治疗脑胶质瘤（Gamma knife radiosurgery for brain gliomas）.doc

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伽玛刀治疗脑胶质瘤（Gamma knife radiosurgery for brain gliomas）

伽玛刀治疗脑胶质瘤（Gamma knife radiosurgery for brain gliomas） Documents from the network, I collected, finishing, and if there are omissions, errors, but also please correct me! Gamma knife radiosurgery for brain gliomas Glioma is a malignant brain tumor derived from neuroepithelial tissue, with a incidence of 40 to 60%, and an incidence of 10/10 10000 / year in adults Gliomas are classified and classified according to WHO: Astrocytoma (1) astrocytoma (WHO grade II) (2) anaplastic astrocytoma (WHO III) (3) glioblastoma (WHO grade IV) (4) astrocytoma of hair cell type (WHO grade I) (5) subependymal giant cell astrocytoma (WHO grade I) II, less glioma (1) less glioma (grade WHO) (2) anaplastic oligodendroglioma (WHO III) Ependymoma, ependymoma (1) ependymoma (WHO grade II); (2) anaplastic ependymoma (WHO III) (3) subependymal ependymoma (WHO grade I) Mixed glioma (1) astrocytomas (WHO grade II) (2) anaplastic oligoastrocytoma (WHO III) V choroid plexus tumor (1) choroid plexus papilloma (WHO grade I) (2) choroid plexus carcinoma (WHO grade III) Embryonal neuroepithelial tumor Medulloblastoma (WHO grade IV) VII pineal tumor Glioma grade I and II belong to benign stage, and grade III and IV belong to malignant stage. Glioma can develop from benign stage to malignant stage in all kinds of treatment during the course of disease The treatment of malignant glioma always has the problem of recurrence and diffusion. The operation can not completely remove the tumor, and the radiotherapy also has the boundary of tumor determination A large number of necrotic cells and hypoxia cells are accumulated in the center of the glioma, which has a strong resistance to radiation Glioma problem surgery or radiation therapy is the real boundary is not clear, consistent with edema around the tumor that have tumor cells, so surgery and radiotherapy are incapable of action; another kind of understanding is tumor cells can obey the nerve fibers, or to glial stem cells and tumor stem cells spread to ot