急性缺血性卒中的血压调控（Blood pressure regulation in acute ischemic stroke）.docVIP

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急性缺血性卒中的血压调控（Blood pressure regulation in acute ischemic stroke）.doc

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急性缺血性卒中的血压调控（Blood pressure regulation in acute ischemic stroke）

急性缺血性卒中的血压调控（Blood pressure regulation in acute ischemic stroke） The mortality rate of stroke is second in the world, accounting for about 9.5% of the total number of deaths, and 167000000 of the cardiovascular and cerebrovascular patients die from stroke every year, 5100000. Stroke mortality in China and Japan is the highest in the world. The number of stroke deaths in China is almost equivalent to the number of stroke deaths in all developed countries. Overall, 2/3 or more stroke deaths occur in developing countries. The initial incidence of stroke was 141-219/10 million. 1/3-1/2 died from the onset of the disease, and about 80% of strokes were ischemic stroke. Ischemic stroke includes TIA, lacunar infarction and cerebral infarction. Once individuals suffer from stroke, the risk factor for recurrent stroke is 8%-12% per year, and the risk of developing MI is 2-3 times higher. Indeed, 30 days after the stroke, patients who had been rescued from the stroke had more chance of dying from cardiovascular disease than those who had died from cerebrovascular events. Therefore, it is necessary to discuss hypertension as a common risk factor for cardiovascular and cerebrovascular diseases. Pathophysiology: The brain weighs about 2% of the body weight, while the brain consumes 10% of the total oxygen consumed by the brain. The normal value of cerebral blood flow (CBF) was about 50ml-55ml/100g/mL, among which the grey matter was 65-75ml/100g/min and the white matter was 35-40ml/100g/min. The total output of the heart is 5000ml/, and the normal blood pressure of the brain is 10% of the total output of the heart, of which the internal carotid artery flow is 300-400ml/, and the vertebral artery flow rate is 200ml/ CBF. When the cerebral vessels gradually become narrow, occlusion or local blood pressure decrease, the cerebral blood flow gradually decreases. Once the perfusion area is lower than that, the brain function and structural disturbance can appear. When the rCBF is 20ml/