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纳多洛尔(Than the parlour)
纳多洛尔(Than the parlour)
Than the parlour
【 drug name 】
Generic name: nadeolol
English common name: Nadolol
Other names: kanggudo, kongardo, naphthalene, naphthol, naphthalene, hydroxynaphthalene, hydroxynaphthalene, Anabet, apo-nadol, Corgard, Nadololum, Solgol
[clinical application]
1. Used for high blood pressure and angina pectoris. (1) it can be used alone or in combination with other drugs. Does (2) does
2. Also used for arrhythmia, ※ (1), myocardial infarction (foreign information), ※ (2), hyperthyroidism, migraines (1), and tremor (foreign information). Does (2) does
【 pharmacology 】
1. Pharmacodynamic nadolol is a non-selective beta epinephrine receptor blocker, membrane stabilization and endogenous pseudosympathetic activity (ISA), low fat solubility. Does (2) does this medicine through competition painted painted painted painted beta 1 and beta 2 receptor binding sites of antagonism of sympathetic the neurotransmitter effect, can make the myocardial contraction force reduces, slow heart rate, cardiac output, lower blood pressure and plasma renin activity decrease. The effect is similar to propranolol, but is 2 to 4 times stronger than propranolol. ※ (1) it is characterized by decreased heart rate, weak myocardial inhibition and the increase of renal blood flow. Does (3) does
A number of studies show that the medicine treatment angina pectoris effectively for a long time, can reduce the dosage of nitroglycerin, to reduce the frequency and severity of angina pectoris attack, increase the intensity and duration), treatment Ⅰ and Ⅱ (mild to moderate hypertension. It is reported that this drug can effectively control the tachycardia, palpitation, neuroticism, hyperactivity and finger tremors associated with hyperthyroidism. However, the efficacy of this drug in the treatment of hyperthyroidism, migraine prevention and therapeutic tremor was not determined. Does (2) does
· action mechanism (1) antihypertensive: decreased cardiac output (negative muscle strength a
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