间苯三酚在结肠镜检查中的应用-中国试验方剂学杂志.DOC

作者简介：赵洁（1972~ ），硕士，副主任医师，研究方向：胃肠道肿瘤。E-mail:zjie1010@163.com effects, the phloroglucinol is safe and effective, so it can be widely used in clinical. 间苯三酚在双气囊小肠镜检查中的应用 赵洁1 李振峰2 毛海洲1 常勤征1 1. 河南省开封市中国人民解放军第一五五中心医院消化内科 2. 郑州大学医学院第二附属医院消化内科 摘要：目的：探讨间苯三酚在双气囊小肠镜检查中的临床效果和应用价值。方法：选择2007年6月至2008年9月在郑州大学二附院行双气囊肠镜检查的36例患者，随机分为间苯三酚组和安慰剂对照组各18例，观察两组患者腹痛情况、小肠镜完成时间和检查前、中、后的血压和心率变化等。结果：两组疼痛值差异无统计学意义。间苯三酚检查完成时间明显短于对照组。各组检查前、中、后收缩压、舒张压及心率差异均无统计学意义。疼痛值和检查完成时间差异无统计学意义。结论：小肠镜检查前及检查中静脉注射间苯三酚，能够部分缓解小肠镜检查的疼痛，缩短检查时间，其作用安全有效，无明显不良反应，可以广泛应用于临床。 关键词 间苯三酚；小肠镜；检查时间 Application of the phloroglucinol in the examination by Double-balloon enteroscopy ZHAO Jie1, LI Zhen-feng2, MAO Hai-zhou1, CHANG Qin-zheng1 1. The gastroenterology of the 155th Central Hospital of PLA, Kaifeng 475003, China 2. The gastroenterology of the 2rd Hospital of Zhengzhou univercity ABSTRACT　Objective:　Analyzing the clinical effects and the values about application of the the trimethyphloroglucin in the double-balloon enteroscopy examination. Methods:　There are 198 patients who accepted the double-balloon enteroscopy examination in the 2rd hospital of Zhengzhou univercity between June 2007 to Semptember 2008. Two groups in random: 18 patients are the testing group and 18 patients in controling group before the operations. We observed the bellyache, enteroscopy completion time and the changes in blood pressure and heart rate before, during and after examination. Results: Two groups have no significant difference in pain scores. Completion time of test (phloroglucinol) group was shorter than that of the control group. Each group checks blood pressure and heart rate before, during and after examination have no significant difference. The difference of pain and the completion time was not statistically significant. Conclusion: The injection of phloroglucinol before double-balloon enteroscopy examination can partly alleviate the pain and shorten the examination time. Without significant side KEY WORDS: phloroglucinol; enteros