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论文创新点： 1、首次把根-土界面的研究和兽药污染联系起来，过去相关的一些研究主要是针对重金属方面的，分析根-土界面一些特有的性质对磺胺类药物毒性效应的影响 2、研究手段，由先前的重视“静态端点”研究转向对把握动态过程的研究，这是研究解决环境污染和生态破坏及其所造成的危害和结果手段的一大进步。 磺胺间甲氧嘧啶在玉米根-土界面毒性研究 摘要：通过根际袋土培试验，研究了磺胺间甲氧嘧啶(SMM)对玉米根际与非根际土壤酶活性和土壤呼吸强度的影响。结果表明，无论是否有根系作用，过氧化氢酶对磺胺间甲氧嘧啶胁迫的反应均不敏感。但在高浓度磺胺间甲氧嘧啶(50 mg·kg- 1)作用下，试验初期对脲酶有明显的抑制作用，而在试验后期则表现出一定的促进作用，且在SMM胁迫下根际效应表现的更为明显的。SMM胁迫对根际与非根际土壤呼吸均有抑制作用，随浓度的浓度增大，抑制作用越明显，由于根际作用，一定程度上缓解了SMM污染对根际微生物的毒害。一般情况下，根际土壤脲酶和过氧化氢酶活性及土壤呼吸强度均要大于非根际土壤，根际效应明显。 关键词:磺胺间甲氧嘧啶；脲酶；过氧化氢酶；土壤呼吸；玉米；根际效应 中图分类号： 文献标识码：AThe Eco-toxicological Effect of Sulfadiazine Sodium on Corn Rhizospheric and Non-rhizospheric Soil Abstract：The effects of sulfadiazine sodium on soil respiration and activities of urease and catalase in corn rhizospheric and non-rhizospheric soil were investigated by using a rhizobx simulating rhizosphere environment. The study showed that sulfadiazine sodium had not significantly changed the catalase activity during the most incubation periods whether lt effected by corn rhizospheric or not. The activity of soil urease was inhibited at the beginning but stimulated afterwards in high dosage concentration of sulfadiazine sodium(50 mg·kg- 1). The rhizosphere soil urease activities of SMM polluted corn lands are higher than those of CK lands, and have a significant rhizosphere effects. Soil respiration was inhibited by sulfadiazine sodium in different degrees in corn rhizospheric and non-rhizospheric soil , the degress of the inhibition had the dose-effect relationship with the concentration of sulfadiazine sodium, the higher of treated concentration of sulfadiazine sodium, the stronger inhibition of soil respiration suffered. SMM was less poisonous to soil respiration with the effect of corn rhizospheric .Meantime, the enzyme activities and soil respiration in rhizospheric soil were higher than that of non-rhizosphere all along , the rhizosphere effect was significant. Keywords: sulfadiazine sodium; urease; catalase; soil respiration; corn; Rhizosphere effect 抗生素被