脑电图及新生儿缺氧缺血性脑病关系探究.docVIP

脑电图及新生儿缺氧缺血性脑病关系探究【摘要】 目的 探讨脑电图与新生儿缺氧缺血性脑病(HIE)的临床及预后的关系。方法 回顾性分析98例临床诊断为HIE的足月新生儿的自然睡眠脑电图的临床资料。结果 选择98例HIE患者(轻度42例，中度33例，重度23例)。轻度HIE患者脑电图异常22例，异常率为52.3%, 中度HIE患者脑电图异常28例，异常率为84.8%,重度HIE患者脑电图异常23例，异常率为100%。轻度、中度、重度HIE患者EEG异常率逐渐升高，组间比较差异有统计学意义(χ?2=5.77，5.68，P0.05)。结论 EEG为临床诊断HIE提供了有价值的客观依据,能客观反映脑功能状态及损害程度。EEG与HIE严重程度有很高的相关性,EEG可作为监测HIE的重要指标。EEG对HIE患者的诊断及临床随访具有重要价值。 【关键词】新生儿缺氧缺血性脑病；脑电图；临床分析 Relativity of EEG and clinical manifestations in hypoxic ischemic encephalopathy of newborn XIA Cai-xia, LI Xiu-hua. Department of EEGs, The People’s Hospital of Gongyi City, Gongyi, 451200, China 【Abstract】 Objective To explore the relativity between electroencephalogram (EEG) and clinical manifestations, their prognosis in hypoxic ischemic encephalopathy (HIE) of newborn. Methods The EEG and prognosis results of 98 newborn patients with HIE in natural sleep were analysed retropectively. Results Among 98 cases HIE of newborn(42 cases of mild HIE，33 cases of middle HIE，23 cases of severe HIE).There were 22 cases abnormal EEGs in mild HIE, abormal rate was 52.3%.There were 28 cases abnormal EEGs in middle HIE, abormal rate was 84.8%; there were 23 cases abnormal EEGs in severe HIE, abormal rate was 100%. The abormal rates were increased steply with the clinical severe degree, the differences between the groups was significant (χ?2=5.77，5.68，P0.05). Conclusion EEG can supply valuable and objective means for dianosis of neonatal HIE. There was relativity between EEG and order of severity of HIE, EEG has an important value for diagnosing and following-up of the patients with HIE. 【Key words】Hypoxic ischemic encephalopathy (HIE) of newborn ; Electroenphalogram(EEG); Clinical analysis 新生儿缺氧缺血性脑病(HIE)是指在围生期窒息导致的缺氧缺血性脑损害。轻者预后良好, 重者可在新生儿期死亡或造成不可逆的脑损害［1］。其脑功能的状态与脑电图(EEG)的表现关系密切, 即EEG对新生儿缺氧缺血性脑损伤的诊断和预后判断具有一定的价值。现将2008年1月至2010年6月被确诊为HIE的98例住院患儿的的HIE程度与脑电图关系进行阐述。 1 资料与方法 1.1 一般资料 98例HIE患儿,男57例,女41例,胎龄均在37周以上,无先天畸形。98例患儿均依据患儿的意识、肌张力、拥抱反射、吸吮反射、惊厥、前囟张力、瞳孔改变、中枢性呼吸衰竭的表现，参