获得性长Q-T间期综合征90例临床研究.docVIP

获得性长Q-T间期综合征90例临床研究【摘要】 目的 分析获得性长Q-T间期综合征的临床特点。方法 对90例获得性长Q-T间期综合征病例的临床资料进行回顾性分析。结果 90例中女60例,男30例,发作尖端扭转型室性心动过速1~7/人,平均3.2次,共计29次的尖端扭转型室性心动过速发作中,6次为电击除颤转复(20.7%),其余自行转复;8例应用异丙肾上腺素静脉滴注使心率维持在90~110/min,随后对其中3例植入临时起博器,给予90~110次/min的频率持续右心室心尖部起博,同时去除诱发因素,如纠正低钾血症,补镁,停用胺碘酮及其他引起Q-T间期延长的药物。结论 获得性长Q-T间期综合征为心源性晕厥愿因之一,常诱发尖端扭转型室性心动过速,补钾、镁为重要错施。 【关键词】 获得性;长Q-T间期;综合征 Clinical Analysis of Acquired oflongQ-T Internal Syndrome MENG Su-fang. NO.6 Peoples Hospital of Zhengzhou City,Zhengzhou 450000,China 【Abstract】 Objective To analyse the acquiredr of longQ-T internal syndrome.Methods The clinical data of 90 cases(60females and 30 males)with acquired of long Q-T internal syndrome were analysed in retrospect.Results Attack siuns tachycards 1~7 times/person,3.2 times in average,29 times in total.In which,6 times for defibrillation transfer back(20.7%),the others transfer back by themselves.And 8 cases of application 作者单位:450000河南省郑州市第六人民医院 of isoproterenol infusion to maintain heart rate at 90~110times.Subs、quently,temporary pacemaker was implanted in the three cases of them to give them 90~110 times/min frequency continuos rightventricular apacial pacing.At the same time,remove the trigger factors,such aslow solution that corrects hypokalemia,magnesium,disable amiadarone,and other drugs causingQ-Tinternalprolongation.Conclusion Acquired long Q-T internal prolongation.ConclusionAcquiredlong Q-T internal syndromeis one of the causes of cardiac syncope,often induced torsades sinus tachycardia,so replenishment of potarssium,magnesium is an important therapeutic measure. 【Key words】 Acquired;LongQ-T internal;Syndrome 获得性长Q-T间期综合征常由代谢异常、药物及某些疾病引起[1],常伴尖端扭转型室性心动过速,严重者可危及生命。 1 资料和方法 1.1 一般资料 我院1990年1月至2010年1月住院患者中诊断为获得性长Q-T间期综合征的患者90例,获得性长Q-T间期综合征有明确继发因素,相关症状及Q-T/Q-TC间期延长,其中女性60例,男性30例.发病年龄4~80岁,从发病到入院病程1~60(平均16 d)。超声心动描记检查均未发现心肌病,均无家族史。基础疾病:心房颤动、房性心动过速、有机磷中毒、脑出血、多发伤。诱发原因:胺碘酮加重、低钾、缺氧、窦性心动过缓、西沙唑、Q-T间期0.51~0.62 s,发作时血清钾2.2~4.1 mind/L。 1.2 方法 治疗:异丙肾上腺素+起博+补钾、